Trimix - prostaglandin e1(alprostadil) dose

[mrlittle99]

I have occasional ED due to performance anxiety. I have used Cialis at 20 mg with good results. I also take antidepressant Prozac at 80 mg which also affects me.

I decided to add a medication for OCD called Clomipramine (Anafranil). Within a week I could not get an erection. I panicked and started to look for stronger ED meds and found Trimix. I also stopped the medication, and my erection came back. Nonetheless I was curious about Trimix.

The first time to took Trimix 6 and it did nothing for me. Again, I panicked and ordered the stronger Trimix STS. I later realized that I missed the Corpus Cavernosa and retook the Trimix 6 and got an 18 minute erection.

Most of the reviews I read indicate they have a formula that has 10-20 mcg dose of PGE at 20 units, and they get a 30-60 minute erection. Not me. The Trimix ST2 has 100 mcg vs 2.5 for Trimix 6. I expected a huge difference but all I got was 12 minutes more.

My results.
Trimix 6 (PGE1 2.5mcg Papaverine 30mg Phentolamine 3mg) - 18 minute erection at 20 units.
Trimix ST2 (PGE1 2.5mcg Papaverine 30mg Phentolamine 3mg) - 30 minute erection at 20 units.

This confused me so I started researching. There are two prescription drugs called Edex and Caverject that only contain PGE1. Their strengths maximum is at 40 mcg.

Everything I can find on proper doses of (PGE1) indicate that the standard does is 10-20mcg.
It seems that any thing over 30mcg of PGE1 is wasted. Am I wrong?

How much PGE1 are you taking? How many units? How long does it work?
Any advice of input would be appreciated.

Research quotes –

“The recommended dose of prostaglandin E1 as treatment for erectile dysfunction has been reported to be 10 to 40 micrograms.”

“More than 80% of the patients attained the maximal response at doses of 20 mcg. or less and less than 20% benefited from a further increase. Based on these results, the effects of prostaglandin E1 appear to be receptor-dependent and prostaglandin E1 monotherapy for impotence could be limited to 20 mcg. or less, since larger amounts offer little additional benefit.”

[bldoink]

It seems that any thing over 30mcg of PGE1 is wasted. Am I wrong?

How much PGE1 are you taking? How many units? How long does it work?

I get the impression that you're undertaking this journey without any real medical supervision. Not good!

I'm confused on the mixes you're experimenting with. Also if you mentioned what your dose of the mixes was I missed it. How many units are you using? How many times have you injected?

If you're using Olympia they do seem to offer a ST2 at 30/3/100. But I don't see the Trimix 6 at 30/3/2.5. I do see a
T-106 at 30/3/25: https://www.olympiapharmacy.com/wp-content/uploads/2019/02/RX-ED-scaled-down.pdf

I only have the brief post you've made to base anything on. However, I'm concerned you may be a bit reckless. Please be careful. If you're just starting this journey please find a good Urologist, hopefully one that also specializes in Men's Sexual Health.