Injections and Cialis together

Sticking a needle Where? Courage, guidance and help.
Nocturne
Posts: 165
Joined: Fri Oct 28, 2016 11:59 pm

Injections and Cialis together

Postby Nocturne » Fri Jun 13, 2025 6:17 am

I know that at least some people here are mixing injections with Cialis, and I want to hear from you. How common is this? I’m on 5-10 mg Cialis every day, in a second bad bout of mostly psychogenic ED in the last 10 years. Really thinking about starting injections but also don’t want to give up the Cialis, in large part due to the heart benefits (I have premature heart disease due to my high Lp(a) levels).
If the Cialis dose is kept consistent, and you dial in your injection dose, is all basically well?
Would really like to enjoy some stress-free, anxiety-free sex again. Would like to be able to be a little more acrobatic than I have been over these last 10 years.
My wife and I are both going through enough other stuff right now that being able to just have regular sex without all the baggage feels like it would be really nice.
Genetically sky-high Lp(a) of 390 led to various heart diseases. Ultra-low testosterone of 120 (now 480 with Clomid) also contributed to ED at age 41. Managing with daily Cialis, but for me, the implant is a "when", not an "if".

Crsprez2
Posts: 10
Joined: Sat May 18, 2024 8:39 am

Re: Injections and Cialis together

Postby Crsprez2 » Fri Jun 13, 2025 6:37 am

I have been on daily 5mg Cialis since 1/2021, after my rad prostatectomy 12/2020. I started trimix 3/2024 and have been injecting multiple times per week ever since. I have not seen a problem. The Cialis helps prevent turtling. I tried going off of Cialis for a week and I had to really work urinating with clothes on.

There is NO erection with just the Cialis.

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GoodWood
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Joined: Sun Jun 16, 2019 1:07 pm

Re: Injections and Cialis together

Postby GoodWood » Fri Jun 13, 2025 6:54 am

I started on pills for almost 5 years. Then switched to injections. As my ED progressed I added pills back in ( Sildinafil and then daily cialis). The pills helped the shots work better.
56yo, NYC. ED started at 40. Pills, then shots for 10 years. 24cm Coloplast Titan w/classic pump by Dr Eid 3/25/2025. Will meet for show & tell.
Implant journal: [url] viewtopic.php?f=6&t=26225[/url]

CanGetItUpButNotOff
Posts: 303
Joined: Mon Sep 20, 2021 1:34 pm

Re: Injections and Cialis together

Postby CanGetItUpButNotOff » Fri Jun 13, 2025 10:26 am

Nocturne wrote:If the Cialis dose is kept consistent, and you dial in your injection dose, is all basically well?
For me, this is the key to preventing priapism from combining the two vasodilators.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

Nocturne
Posts: 165
Joined: Fri Oct 28, 2016 11:59 pm

Re: Injections and Cialis together

Postby Nocturne » Fri Jun 13, 2025 2:49 pm

GoodWood wrote:I started on pills for almost 5 years. Then switched to injections. As my ED progressed I added pills back in ( Sildinafil and then daily cialis). The pills helped the shots work better.


Was your ED psychogenic or due to something else? This is driving me nuts because at this point I’m basically able to get hard and masturbate without much trouble with the Cialis alone, but I seem to subconsciously freak out when I’m with my wife, and in any event I’m just not able to do as much in bed as I could years ago without losing it even at the best of times.

“Psychogenic” isn’t the whole story, it’s more like “your jalopy dick works OK so long as everything else is going well…”
Genetically sky-high Lp(a) of 390 led to various heart diseases. Ultra-low testosterone of 120 (now 480 with Clomid) also contributed to ED at age 41. Managing with daily Cialis, but for me, the implant is a "when", not an "if".

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GoodWood
Posts: 1134
Joined: Sun Jun 16, 2019 1:07 pm

Re: Injections and Cialis together

Postby GoodWood » Sat Jun 14, 2025 7:11 am

Nocturne wrote:
GoodWood wrote:I started on pills for almost 5 years. Then switched to injections. As my ED progressed I added pills back in ( Sildinafil and then daily cialis). The pills helped the shots work better.


Was your ED psychogenic or due to something else? This is driving me nuts because at this point I’m basically able to get hard and masturbate without much trouble with the Cialis alone, but I seem to subconsciously freak out when I’m with my wife, and in any event I’m just not able to do as much in bed as I could years ago without losing it even at the best of times.

“Psychogenic” isn’t the whole story, it’s more like “your jalopy dick works OK so long as everything else is going well…”



Sometimes ED is sudden and total (example: severed nerves from a prostatectomy surgery) but usual it’s gradual and progressive. It’s no surprise that your dick could work fine for masturbation but not with a partner. With masturbation the focus/pleasure is entirely focused on me. But sex with partner splits the focus and pleasure. The split focus/pleasure might not be enough to keep me hard while the total focus could. But that doesn’t mean the cause the the ED is psychogenic.

My first Doppler scan was in my (implant) preop exam and was largely done for insurance justification. Prior urologists were not interested in a Doppler scan and I agree with them. It doesn’t matter what the scan shows (nothing, arterial insufficiency, venous leak, a combination) because the treatment is the same. Pills, shots, implant.

I think MANY men are hard on themselves, blaming themselves that their ED is psychogenic and if they could just change how they think or get over their anxiety their cock would be fine. But the reality is the underlying cause is organic and not in our (mental) control. We can’t think our way past venous leak.

My advice to guys struggling with ED is to efficiently work their way through the (legitimate) treatment options: pills, shots, implants. Skip gainswave, skip PRP shots, don’t waste your money on grifters. Don’t wait for treatments in development. Get back to having great sex NOW.
56yo, NYC. ED started at 40. Pills, then shots for 10 years. 24cm Coloplast Titan w/classic pump by Dr Eid 3/25/2025. Will meet for show & tell.
Implant journal: [url] viewtopic.php?f=6&t=26225[/url]


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