For the brothers that need/want glans engorgement, I thought I would report that I continue to be VERY impressed with Misoprostol for that purpose, which increases my sensitivity and enables orgasms. I have now used it about a dozen times and it has worked as well as Trimix gel which I also have used about a dozen times.
In my personal view, here are the comparisons between the two:
Trimix gel (2 ml with 2500 mcg of PGE plus other components of Trimix): About $20 per dose of 0.3 ml (insurance doesn’t cover it), has to be inserted into the urethra and held straight up until it’s absorbed – maybe 15 minutes or so, then takes about 20-30 minutes to take effect. Good glans engorgement. Effect lasts for about 2 hours. Needs to be refrigerated.
Misoprostol (a generic med which is a PGE analog): about $0.66 per dose (with my Medicare insurance) of 400 mcg paste from pills, can be painted mostly on the glans and some on the shaft, can put a condom on and go about your business for about 45 mins to an hour while it takes effect. Good glans engorgement and half inch increase in girth. Effect lasts for more than 3 hours. Doesn't need to be refrigerated -- can prepare several batches in air tight containers for future use.
So obviously, to me Misoprostol is the clear winner. If anyone has differing opinions, please speak up. And if anyone wants more details on how to use it, just pm me.
Trimix Gel vs Misoprostol -- My Experience
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Trimix Gel vs Misoprostol -- My Experience
75, used pills, injections -- all lost effectiveness. Titan implanted by Eid in Feb '22.
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Re: Trimix Gel vs Misoprostol -- My Experience
Thanks for the info. I’ve got a one month supply. How do I make the paste?
67 yr old, married 24 yrs,
Cialis, Trimix since 2004
MIA in 2004
Implanted by Dr Guise on 10/28/21
Pre-op: 6.3" length 6" girth
14 mos post op: 6.5" lento and 6" girth
Revison done by Dr Perito 5/14/25 with a AMS 21+1 LGX
Cialis, Trimix since 2004
MIA in 2004
Implanted by Dr Guise on 10/28/21
Pre-op: 6.3" length 6" girth
14 mos post op: 6.5" lento and 6" girth
Revison done by Dr Perito 5/14/25 with a AMS 21+1 LGX
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- Posts: 566
- Joined: Thu Feb 18, 2021 4:22 pm
Re: Trimix Gel vs Misoprostol -- My Experience
I will pm you with the details
75, used pills, injections -- all lost effectiveness. Titan implanted by Eid in Feb '22.
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- Joined: Wed Mar 25, 2020 11:18 am
Re: Trimix Gel vs Misoprostol -- My Experience
Has anyone here other than crazyjoe tried misoprostol for glans swelling?
56, DE since 2010, the pills worked at high doses not well, on 01/23/23 titan one touch 22, Dr. Gabriele Antonini, Replacement from titan to cx 21 with ms pump on 04/03/2025, today I am almost 60 years old and have various pathologies, testosterone
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