June 2025 - 16 MPP adverse events reported to FDA

The final frontier. Deciding when, if and how.
Rowand6000
Posts: 22
Joined: Sat May 24, 2025 9:26 am

Re: June 2025 - 16 MPP failure events reported to FDA

Postby Rowand6000 » Sat Aug 02, 2025 1:04 pm

LastHope wrote:Thank you Chuck and Duke for your inputs! I appreciate that.

F1 - You're right! Hormonal manipulation is a great variable to control. As mentioned in the other post, I'm experimenting with caborgoline and clomid to tweak my prolactin, T and dopamine.



Hello,

Any advice on how to increase the dopamine? I tried bupropion but it gave me vertigo.

L tyrosine? Nicotine gummies? High dose caffeine? Methylene Blue?

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duke_cicero
Posts: 407
Joined: Tue May 28, 2024 2:58 pm

Re: June 2025 - 16 MPP failure events reported to FDA

Postby duke_cicero » Sat Aug 02, 2025 1:27 pm

Rowand6000 wrote:
LastHope wrote:Thank you Chuck and Duke for your inputs! I appreciate that.

F1 - You're right! Hormonal manipulation is a great variable to control. As mentioned in the other post, I'm experimenting with caborgoline and clomid to tweak my prolactin, T and dopamine.



Hello,

Any advice on how to increase the dopamine? I tried bupropion but it gave me vertigo.

L tyrosine? Nicotine gummies? High dose caffeine? Methylene Blue?


L-tyrosine and rhodiola rosea are a nice and generally safe combo. You might try splitting l-tyrosine 1/2 and 1/2 over the course of the day. Once upon waking, once early afternoon.

Also, bupropion is pretty weak on dopamine. Mainly it's a norepinephrine booster. I had to stop using it because it gave me memory loss, specifically verbal memory. I was forgetting things right in the middle of my sentences. Bupropion is a noncompetitive antagonist at nicotinic acetylcholine receptors, which are responsible for learning and memory...
Born 1990. ED since age 20 after a bicycle accident. Coloplast Genesis malleable implanted December 2024 by the great Dr. Laurence Levine in Chicago.

· December 2024 implant journal
· June 2025 update

ready2go
Posts: 695
Joined: Fri Aug 25, 2023 7:47 pm

Re: June 2025 - 16 MPP adverse events reported to FDA

Postby ready2go » Sat Aug 02, 2025 8:49 pm

tooyoung wrote:
easymoney wrote:Anyone know why Rigicon does Rigicon does not report? I'm due to go back to my surgeon on the 15th and I'm going to ask him to declare my implant as failed due to it not bending properly. Anyone want to bet the pushback from the surgeon I'm going to get?


Commonly tactra or rgi10 don't bend..or even bend at all...even though companies and doctors claim otherwise..shit rigiCON even claims that it bends 130° (beyond the scrotum).. And still idealist carcasses here say "these devices are approved by the holy FDA".."in surgeon we trust"..."if you were right, lawyers would bankrupt these companies"..."you are a troll".

They don't know they are the trolls themselves for preventing any attempt of critical appraisal...and they will realize asslicking doesn't bring them any good.

Watch this comedy clip

https://youtu.be/CKMuMm4ZAok?si=7YRNQ5-FIZrSAM5A
(The surgeon is skilled though)

If companies and FDA say it bends , then it bends :lol:

What's strange though is that patients distrust their eyes and their own brain and keep reiterating what they have been told.

ASS LICKING CARCASSES ARE THE TROLLS

Anyway..If I were you , I wouldn't consider it as a failure as long as it penetrates well...and will adapt to its' subpar bending ability (if there's one at all)...undergoing another surgery isn't good as you know.


My tactra bends by itself ,and did so from day one .
in fact i need to hold it for it to stay up horizontal
American , retired in the philippines .
tactra malleable 13 mm ,in new delhi India . on april 2024

ready2go
Posts: 695
Joined: Fri Aug 25, 2023 7:47 pm

Re: June 2025 - 16 MPP adverse events reported to FDA

Postby ready2go » Sat Aug 02, 2025 8:50 pm

easymoney wrote:Anyone know why Rigicon does Rigicon does not report? I'm due to go back to my surgeon on the 15th and I'm going to ask him to declare my implant as failed due to it not bending properly. Anyone want to bet the pushback from the surgeon I'm going to get?


you can not get it to stay bent in the down position ?
American , retired in the philippines .
tactra malleable 13 mm ,in new delhi India . on april 2024

Rowand6000
Posts: 22
Joined: Sat May 24, 2025 9:26 am

Re: June 2025 - 16 MPP failure events reported to FDA

Postby Rowand6000 » Sat Aug 02, 2025 9:27 pm

duke_cicero wrote:
Rowand6000 wrote:
LastHope wrote:Thank you Chuck and Duke for your inputs! I appreciate that.

F1 - You're right! Hormonal manipulation is a great variable to control. As mentioned in the other post, I'm experimenting with caborgoline and clomid to tweak my prolactin, T and dopamine.



Hello,

Any advice on how to increase the dopamine? I tried bupropion but it gave me vertigo.

L tyrosine? Nicotine gummies? High dose caffeine? Methylene Blue?


L-tyrosine and rhodiola rosea are a nice and generally safe combo. You might try splitting l-tyrosine 1/2 and 1/2 over the course of the day. Once upon waking, once early afternoon.

Also, bupropion is pretty weak on dopamine. Mainly it's a norepinephrine booster. I had to stop using it because it gave me memory loss, specifically verbal memory. I was forgetting things right in the middle of my sentences. Bupropion is a noncompetitive antagonist at nicotinic acetylcholine receptors, which are responsible for learning and memory...




What dosage do you use for l tyrosine and rhodiola rosea?

Have you heard of apormorphine? Its approved for ed in europe. Works on dopamine to give an erection apparently

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duke_cicero
Posts: 407
Joined: Tue May 28, 2024 2:58 pm

Re: June 2025 - 16 MPP failure events reported to FDA

Postby duke_cicero » Sat Aug 02, 2025 9:32 pm

Rowand6000 wrote:
duke_cicero wrote:
Rowand6000 wrote:

Hello,

Any advice on how to increase the dopamine? I tried bupropion but it gave me vertigo.

L tyrosine? Nicotine gummies? High dose caffeine? Methylene Blue?


L-tyrosine and rhodiola rosea are a nice and generally safe combo. You might try splitting l-tyrosine 1/2 and 1/2 over the course of the day. Once upon waking, once early afternoon.

Also, bupropion is pretty weak on dopamine. Mainly it's a norepinephrine booster. I had to stop using it because it gave me memory loss, specifically verbal memory. I was forgetting things right in the middle of my sentences. Bupropion is a noncompetitive antagonist at nicotinic acetylcholine receptors, which are responsible for learning and memory...




What dosage do you use for l tyrosine and rhodiola rosea?

Have you heard of apormorphine? Its approved for ed in europe. Works on dopamine to give an erection apparently


500mg l-tyrosine 2x daily, 500mg rhodiola once daily. Haven't heard of apormorphine!
Born 1990. ED since age 20 after a bicycle accident. Coloplast Genesis malleable implanted December 2024 by the great Dr. Laurence Levine in Chicago.

· December 2024 implant journal
· June 2025 update

LastHope
Posts: 1466
Joined: Sun Feb 18, 2024 1:26 am

Re: June 2025 - 16 MPP failure events reported to FDA

Postby LastHope » Tue Aug 19, 2025 10:58 pm

duke_cicero wrote:Cabergoline is really potent stuff. So is clomid. Is there a reason you're taking clomid over enclomiphene?


Cabergoline’s GI side effects (gastric) are brutal. Clomid is FDA approved and covered by my insurance and dirt cheap unlike enclomiphene.

LastHope
Posts: 1466
Joined: Sun Feb 18, 2024 1:26 am

Re: June 2025 - 16 MPP failure events reported to FDA

Postby LastHope » Tue Aug 19, 2025 11:09 pm

thedriver wrote:
LastHope wrote:
duke_cicero wrote:
I can't think of a physiological reason why an IPP would enhance climax, though.


I thought the same. I have a few hunches though:

1) Will partial inflation to 75–80% have any positive effect?
2) Will the deflated state relax my nerves better compared to 24/7 stretching?
3) Will increased tunica stretch and girth provide more stimulation by rubbing more thoroughly inside the vagina?
4) Will additional surgery only make things worse? Something I don't want!


I'm just the opposite, I can orgasm 2 to 3 times through out a couple hour session with my MPP, I think I was over inflating when I had my IPP's, and found that if I only pumped to 80% I had much more feeling in my glans area and was able to orgasm then, now with the MPP there seems to be a much more natural feeling to everything and I actually have trouble holding back.
I know deflating a IPP just to get back some feeling in the glans area is sort of self defeating the purpose of the IPP, but if you can't orgasm, what's the point of it ?
I also find that it really matters what you might have laid out in front of you at the time,,,, I'm lucky to have a wifey that loves to lay around and tease me through out the day.


Thank you thedriver for your inputs! Your points make total sense. You're a lucky man.

LastHope
Posts: 1466
Joined: Sun Feb 18, 2024 1:26 am

Re: June 2025 - 16 MPP adverse events reported to FDA

Postby LastHope » Wed Aug 20, 2025 12:03 am

tooyoung wrote:
Rowand6000 wrote:
LastHope wrote:Attached.

June 2025 MPP adverse events reported to US FDA.

AMS Tactra - 10
AMS Spectra - 2
Coloplast Genesis - 4



Does this mean Rigi10 is “the safest bet” for MPP patients?

Even online searches show Rigi10 having the least amount of problems.


Rigicon doesn't report to MAUDE.

Which also shows how not all failures are reported on MAUDE.


Rigicon seems to have started reporting Rigi10 events after seeing your post. Thanks for bringing this up! I'm glad they are listening.

Thisworld
Posts: 270
Joined: Sun Sep 06, 2020 3:01 pm

Re: June 2025 - 16 MPP adverse events reported to FDA

Postby Thisworld » Sun Aug 24, 2025 9:33 am

I think this is relevant to the thread. I spotted on eduardo bertero website, under the voice -malleable disadvantages "Disadvantages include occasional difficulty in concealing it and the performance of transurethral endoscopic procedures that may require perineal urethrostomy." Can someone explain what that wuold mean? A malleable wuold increase chances of urethrostomy?

https://urologia-sp.com.br/protese-peni ... 37cea-815f
Hard flaccid syndrome since 2019. Trying to get better with conservative treatments but an implant is on my radar


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