Breast implant illness/silicone toxicity/autoimmunity

[Thisworld]

One if the reasons i went for the implant, i cant keep waiting for a cure for HF, sooner or later i had to move on, didnt feel good getting close to 30 and never having a good sexual experiance.

Yeah I can't imagine living 16 years with ED, it must have been awful. You totally made the right choice, especially considering that after so many years the chances to "cure" your HF naturally (if that wuold never be possible) were anyways pretty unrealistic

[Musson]

The silicone breast implant sensitivity was scientifically debunked. The problem is that the irrefutable science came in after Dow/Corning had already entered into a very large settlement of the class action litigation. Timing is everything and in this case Dow/Corning settled too soon.

[nuance]

The silicone breast implant sensitivity was scientifically debunked. The problem is that the irrefutable science came in after Dow/Corning had already entered into a very large settlement of the class action litigation. Timing is everything and in this case Dow/Corning settled too soon.

What turned out to be the reason for the auto-immune disease in these cases?

[Lost Sheep]

The silicone breast implant sensitivity was scientifically debunked. The problem is that the irrefutable science came in after Dow/Corning had already entered into a very large settlement of the class action litigation. Timing is everything and in this case Dow/Corning settled too soon.

Please cite sources.

[Gt1956]

The silicone breast implant sensitivity was scientifically debunked. The problem is that the irrefutable science came in after Dow/Corning had already entered into a very large settlement of the class action litigation. Timing is everything and in this case Dow/Corning settled too soon.

Please cite sources.

Not really proof. But I remember that several of the implant models that were temporally banned were later approved.
Lots of hysteria was involved. My SIL went through it because she had breast reconstruction. My take on her issues was a a matter of rejection rather than a silicone issue. But she had them removed & never replaced them
After the moratorium on implants was lifted. Many women had thiers swapped out for the new approved models.
As I've posted. I read of a silicone sensitivity test that can be performed. But it is under utilized.

[Gt1956]

A quick search found this.
In 1997, the U.S. Department of Health and Human Services (HHS) appointed the Institute of Medicine (IOM) of the U.S. National Academy of Sciences (NAS) to investigate the potential risks of operative and post-operative complications from the emplacement of silicone breast implants. The IOM's review of the safety and efficacy of silicone gel-filled breast implants, reported that the "evidence suggests diseases or conditions, such as connective tissue diseases, cancer, neurological diseases, or other systemic complaints or conditions are no more common in women with breast implants, than in women without implants" subsequent studies and systemic review found no causal link between silicone breast implants and disease.

[nuance]

Somewhat relevant to the topic is the issue of implant-related cancers, e.g. ALCL (anaplastic large-cell lymphoma):

Dr Gould has also found a case of facial nerve stimulator implant-associated ALCL and a separate case of penile prosthesis-associated ALCL

https://www.cancertherapyadvisor.com/ho ... er-risk/2/

This article is interesting:

" The recall was a reversal of the FDA’s previous position that the implants should be kept on the market – and came on the heels of headlines about the agency’s failure to disclose thousands of breast implant-associated injuries and complications"

"Latency periods (lag times) between implantation and BIA-ALCL diagnosis have varied widely, from approximately 2 years to 27 years, with a mean lag time of 9.75 years"

Given the mean lag time of approx 10 years, is there enough data on penile implants?

[Musson]

Lost,

Here is the most comprehensive compendium of sources.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882356/

I was heavily involved in the litigation through my work but that was over 20 years ago the exact details are a little fuzzy. The lead plaintiff as I recall had lupus and she was able to throw a lot of symptoms at the wall and a few of them resonated with the court. The better science came in post settlement and created a multi billion fund which continued to feed the litigation machine.

[TANGERINE]

i was just reading about coloplast titan from the manufacturer.

Just to remind everyone

Titan is made of "bioflex" (I think that is a plastic)

AMS is made of "silicon" (that is why it is more pliable in the soft state, also the silicon is not as durable as the plastic bioflex --so say some surgeons with regards to the LGX from ams

So if you are scared of siicon (I would not be) then consider titan.
Also, some people, super rare, state that they get allergic to the antibiotic coating of AMS, so that might be a reason to go titan (no anntibiotic coating); but, on the other hand, the antibiotic coating on AMS might make it infection resistant----and that would be an awesome thing if it panned out (which many argue it has not)

[newbie443]

My understanding is that all implant cylinders are coated with an antibiotic solution before placed in the man. AMS does the coating during the manufacturing process and is said to be deeper in the material. Coloplast cylinders are manufactured with a substance that they say permits the antibiotic solution to be absorbed quickly in the OR at the time of the surgery. This permits the doctor to choose the antibiotic solution to use. There were higher infection rates when this first came out with Coloplast and the then recommended solution. But the solution was quickly changed and using the current solution Coloplast has the same infection rate as the AMS coating. There was a paper I read on this but I do not have a copy saved.