Should I get an implant?

[Kodixx]

macoza, so first, full disclosure, offering specific medical advice is way above my pay-grade I am not a medical professional and all I'm offering is info I've picked up along the way. So please take anything I say with a grain of salt. Yes, I believe numbness and lack of sexual sensitivity seem to be two separate things. If it were true numbness, I would talk it over with my urologist, then if he/she agreed, likely turn to a qualified neurologist to evaluate the physical nerves. When I say "qualified", I mean someone with experience doing that in the context of "men's health".

Other guys have referred to issues with sexual sensitivity as the "brain-dick connection". And that can be lots of stuff -- libido, T, how your brain processes sexual thoughts, maybe some issue with how the brain and nerves are processing physical stimulation. My Dr told me, and lots of guys here have posted, that sexual sensitivity is often impaired following the implant surgery, and improves over time. I've experienced that, with sexual sensitivity improving between the surgery and 5+ months post-op. Will it get back to where it was before ? Don't know. Hope so.

In your case, maybe something about the Trimix therapy shocked the nerves and temporarily changed how they function or communicate with the brain ? What do do first ? Again I'd check in with my urologist and PCP first. But like most things I'd probably start with what's easiest and least invasive -- and less expensive. I've thought about talking to multiple "men's health" clinics and compare their answers to see what I can learn. Since they've likely had many patients using Trimix they might have experience with side effects that might compare to your situation. Maybe they'd have some kind of screening process to isolate the issue(s) better ?

Best wishes for navigating this and the fastest path to resolution. I'd be anxious to hear how things go !

- Chuck

What kind of specialist do I see for possible nerve damage of the penis? Btw, the link talks about numbness. I don't feel numbness on my penis after touching it everywhere. Is it possible that I had incurred some internal nerve damage from injecting trimix? My uro says no. Just so you know, the last time I felt sexual sensation was about 6 weeks ago when I masterbated and ejaculated. Since that time, I've been unable to feel sexual sensation or orgasm. What do you suggest I do?

[LastHope]

I struggled with non-spontaneous, dose-dependent, unreliable (for me) and quality-of-life-reducing ED pharmacotherapy for 20 years of my precious irreversible youth. Life is too short. Get the implant and optimize your existence. .

Hi lasthope,

Very sorry to hear about the stupid med that wrecked your life dude. I know exactly what you went through, it's very hard. I have 2 questions...

1. Are you able to feel arousal and good libido with your implant?

2. I took viagra 3 weeks ago and was able to get erect. But I didn't feel sexual sensation in my penis. Yet I read that you need to be sexually with excited for viagra to work. But in my case I got erect without feeling sexually excited. What do you make of this and what do you suggest?

.

Hey macoza, my libido and arousal continue to be great with my implant. It's higher now with a 24/7 boner.

If there's one disappointment, I would say it's delayed orgasm during PIV. This won't be a complaint if a partner wants me to last too long in bed! I haven't experimented with different partners other than my wife , so let's just say it's somewhat of a subjective complaint. Some may call it a happy accident. I hope my sensitivity progresses with time. I'm not asking for PE. I just want the ability to orgasm in 15-20 minutes with PIV and without the use of external aids like sex toys.

In your case, I think Viagra results in sustained cGMP levels and causes an erection. Even by injecting Trimix, it's possible to get erection without sexual stimulation.

Mechanism of action:
Sexual Stimulation and Nitric Oxide Release:
When sexually stimulated, nitric oxide (NO) is released in the corpus cavernosum (the spongy tissue in the penis responsible for erections).

cGMP Production:
NO then activates an enzyme called guanylate cyclase, which in turn leads to increased production of cyclic guanosine monophosphate (cGMP).

Smooth Muscle Relaxation and Blood Flow:
cGMP is a chemical messenger that causes the smooth muscles in the penis to relax, allowing for increased blood flow into the corpus cavernosum, leading to an erection.

PDE5:
Under normal circumstances, PDE5 is responsible for breaking down cGMP, thus ending the erection.

PDE5 inhibitor
PDE5 inhibitor, blocks the action of PDE5. This prevents the breakdown of cGMP, maintaining higher levels of cGMP in the corpus cavernosum.

Enhanced Erection:
With sustained levels of cGMP, the smooth muscle relaxation and increased blood flow continue, making it easier to achieve and maintain an erection during sexual stimulation.