New Mix - Numbing/Sore Sensation

Sticking a needle Where? Courage, guidance and help.
ragnar35
Posts: 17
Joined: Tue Jan 23, 2018 12:35 pm
Location: Tampa

New Mix - Numbing/Sore Sensation

Postby ragnar35 » Mon Feb 12, 2018 1:37 pm

I was on the most basic bi-mix with mediocre results. The doc bumped me up to the first Tri-Mix solution - 10mcg/30mg/1mg - I tried it twice - and found that I got a more rigid erection, but it was a sore (and slightly numb) erection. It was to the point that I couldn't achieve an orgasm. Anyone have a similar experience?
63 years old, male, low-grade prostate cancer active surveillance only, ED for 40 years, injecting trimix. VED's don't work. Dr. Raphael Carrion at TGH. Considering implant surgery.

oldbeek
Posts: 2579
Joined: Sun Sep 10, 2017 1:46 pm
Location: Los Angeles area

Re: New Mix - Numbing/Sore Sensation

Postby oldbeek » Mon Feb 12, 2018 9:55 pm

The pge1 in trimix gives me a extreme pain. So sore I do not want to use it. This is common in 30% of the guys trying it according to my URO and lab that makes it. I thought I could handle a very small amount of trimix. (5units or less mixed with 22 units of 30-1 bi mix) Last try I used 3 units of tri with 22 units of bi. Painfull 3 hr erection. Why didn't the dr move you to 30-2 bi mix? I am going to 30-2 and never use trimix again. Implant consultation on march 12.
83, good health, RP 7-2017, all nerves taken , PSA 0.05in 2025,, implanted 4-1-18, Infra-pubic, AMS lgx 15 cm with 5cm rte. Implant at USC Keck. Dr Boyd and Dr Loh Doyle 6.5 x 5, 800 AUS 7-21-20 at Keck

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bldoink
Posts: 4081
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: New Mix - Numbing/Sore Sensation

Postby bldoink » Tue Feb 13, 2018 12:34 am

ragnar,
At a high enough dosage I'll get the pain but I obviously don't experience it at the level others do. The pge1/alprostadil is the most effective ingredient of trimix. If the erection was much better you might want to try backing off the dosage to see if you can find a sweet spot between pain and effectiveness.
Good luck
RRP 2011 Mayo Jacksonville, Dr. Wehle. Non nerve sparing. C in margins. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ 7 - 16 units. Originally Edex20 or 40, then compounded PGE1 due to cost. Inject. 14 yrs. It works. FL Treasure coast.

jeff65
Posts: 17
Joined: Fri Dec 29, 2017 1:47 pm
Location: Central NC

Re: New Mix - Numbing/Sore Sensation

Postby jeff65 » Tue Feb 13, 2018 10:39 am

I have some aching with trimix as well but not severe. I’m still trying to find the minimum dosage I can use and still get good results. My last dosage was 15 units of the formula in my sig which is a lower strength formula. Good results but lasted a little longer than I would prefer. Trying 10 units next time.
53 yo, married 31 years. DX with prostate cancer on Aug 28, 2017. RALP on Oct 30, 2017 with bilateral nerve sparing. Cancer-free but with ED without meds. Taking 40mg sildenafil daily and 10 units trimix (16.7mg pap; .56mg phent; 5.6 mcg PGE1) 1-2x/week.

ragnar35
Posts: 17
Joined: Tue Jan 23, 2018 12:35 pm
Location: Tampa

Re: New Mix - Numbing/Sore Sensation

Postby ragnar35 » Wed Feb 14, 2018 4:25 pm

Appreciate the suggestions and insight. I have contacted the doc about a stronger BiMix, and hope that will do the trick.
63 years old, male, low-grade prostate cancer active surveillance only, ED for 40 years, injecting trimix. VED's don't work. Dr. Raphael Carrion at TGH. Considering implant surgery.

graymare
Posts: 110
Joined: Thu Feb 19, 2015 3:50 pm

Re: New Mix - Numbing/Sore Sensation

Postby graymare » Wed Feb 14, 2018 7:02 pm

This was talked about in an earlier thread on FT. The link below will show you conversations on the topic

viewtopic.php?f=5&t=2392&p=41467#p41467
Married, ED for 28 yrs. On Trimix for many yrs. Lived in the Adirondacks of NY but moved south. Cancerous prostate removed in 2023. Hernia (from prostate surgery) repaired in 2024. Urinary sling implanted 2025.


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