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I'm fairly new to injections - 4 months - regularly every 3 or 4 days. Is a 30/3/20 Tri-Mix. I do all the recommended procedures of varying the injection site, cleanly inserting the needle at a 90° angle, compressing the site, etc. Only very infrequent bruising so I think I'm doing a pretty good job. But I am paranoid about scarring.

I regularly - quarterly - have my urologist check for any signs of problems and see nothing so far. But, then again, I'm only 4 months into it. My question is about early detection of scarring. If fibrosis is occurring, will a trained urologist be able to detect it in time for me to enact preventive measures? Or is it more like, "Oops, you've got peyronies! Too late."

I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ

RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ

Fibrosis=scarring

wolfpacker wrote:

RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ

Fibrosis=scarring

Can you speck me? I have 32 years old!!

If you want to be proactive about scarring. I recommend that you pump every day (not necessarily the day after an injection) this allows your penis to stay healthy and helps make sure that scarring does not form.

Bambino09 wrote:

wolfpacker wrote:

RJ_in_Pa wrote:I noticed and my Uro confirmed that I have fibrosis. Feels like a vein running along the left side of my penis, but it’s definitely not a vein. My Uro said it is not uncommon for those that had an RP to have fibrosis due to the trauma from the surgery.

I have never heard that there is a connection between fibrosis and PD. I was under the impression that PD was caused by scarring, but not sure how Pd is caused by injections.

Can anyone give us some insight on this?

Thanks,
RJ

Fibrosis=scarring

Can you speck me? I have 32 years old!!

Speck you? I'm not sure what you mean.

misterecz wrote:If you want to be proactive about scarring. I recommend that you pump every day (not necessarily the day after an injection) this allows your penis to stay healthy and helps make sure that scarring does not form.

I do pump pretty regularly, probably 4 or 5 days each week.

As a further data point, I note that different urologists have different opinions on the cause of scarring. I personally see two different urologists and each one of them says that the chemicals are not likely to cause scarring but just poor injection technique that causes trauma to the tunica. OTOH, there are reports here (frequently quoting Dr. Eid) that implant patients usually, or often, present with scarring from Past ICI with Tri-Mix, but not so much from just Alprostadil mono-mix. Separately, I wrote another doctor who performs a lot of implants and asked the question; his response:

Corporal fibrosis from a history of ICI use is extremely common. I attribute it to the compounds being used rather than the mechanical action of the needle itself.

I can't think of any topic that has such widely diverse opinions from the experts.

misterecz wrote:If you want to be proactive about scarring. I recommend that you pump every day (not necessarily the day after an injection) this allows your penis to stay healthy and helps make sure that scarring does not form.

This has been my routine for over 10 years after I had a bit of a scare with fibrosis after injecting for one year. VED Therapy will aide in healing the injection site by insuring oxygenated blood gets into the penis..Just as stated above, don't use a VED the day after you inject. I pump for 10 seconds, then release for 10 seconds...I do this for 10-12 minutes every other day..

qcswral wrote:Just as stated above, don't use a VED the day after you inject.

I hadn't noticed that suggestion. What is wrong with pumping the day after injecting?

qcswral wrote:I pump for 10 seconds, then release for 10 seconds...I do this for 10-12 minutes every other day..

Another novel thought Every time I see a VED recommendation, I search to see what the recommended protocol is and I find no consensus. My compromise is typically 3 minutes on, 1 minute off for a minimum of 5 cycles.

CanGetItUpButNotOff wrote:

qcswral wrote:Just as stated above, don't use a VED the day after you inject.

I hadn't noticed that suggestion. What is wrong with pumping the day after injecting?

qcswral wrote:I pump for 10 seconds, then release for 10 seconds...I do this for 10-12 minutes every other day..

Another novel thought Every time I see a VED recommendation, I search to see what the recommended protocol is and I find no consensus. My compromise is typically 3 minutes on, 1 minute off for a minimum of 5 cycles.

THe rationale behind not pumping the day after you inject as far as I understand is, your stretching the tissue that is in the process of healing...and possibly causing more minor tares in the tissue. There is a protocol on the Peyronie's web-site, which is similar to this site as it's a forum for discussion. I haven't been on there in a while, but a guy who goes by the user name "Old Man" spelled out his protocol and how successful he's been at like age 85..
When I detected some fibrosis it felt like a pea size nodule on the left side of my penis. It was rather hard when I massaged it. At that time I went to another urologist who was reportedly a Peyronie's specialist. His prescription to prevent further scarring and to stop the development of the nodules to Peyronie's was the following.

1. Inject for the foreseeable future only once a week or less..
2. 400mgs OD of Pentoxifylene ( a blood thinner to promote healing- it's usually prescribed for PAD..which is narrowing of the veins and arteries in your lower extremities)
3. Vitamin E daily..( sorry cannot re-call the dosage)
4. Twice a day of VED treatment until the nodule is resolved...the protocol I used was like 15 minutes per session...

As per this Urologist he told me the nodule was not yet at the point of forming permanent scar tissue...or developing into Peyronie's ...
After 6 months of the above medication and VED protocol, the nodule resolved.. I then went to VED treatments once a day as a prophylactic to causing any further scarring or fibrosis. I have been incident free since which is like 10 years now...Ask your urologist to teach you how to self examine yourself for fibrosis..it's only a matter of squeezing your penis starting from the base to the head and feeling for any hardness, or nodules.

Now here's the wild card in all this....This Peyronie's specialist explained to me that some people are much more prone to developing Peyronie's disease and "they" meaning doctors don't know why..he also told me many Peyronie's or fibrosis issues resolve over time on their own..again, "they" don't know why this is, except the body has a unique ability to heal itself..Sorry for the length of this but I felt it important to explain..Good Luck to you