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To reduce the impact of injections, the advice I received is to press down on the injection site.

But I was never told for how long? 30 seconds, 90 seconds, 5 minutes,

Also, I've been told to massage the area to ensure the mix moves through the penis.

I think this is a good idea, as I've read that Trimix is slightly acidic. Again, for how long should that be done?

I press on the injection site while massaging it in. I've never actually timed it. I'm guessing only a couple of minutes. It also depends on how quickly you naturally clot. If you're on thinners you'll need to keep pressure on the site longer. The gauge of the needle also makes a difference. A bigger hole calls for longer compression.

I press directly on the injection site using an alcohol wipe for about 30 seconds. I then massage full length of penis about 2 minutes while walking around. Then I lay down with iPad and watch porn for about 5 minutes. By then is usually kicking in.

Never timed it either but I am guessing not more than a couple minutes and then
of course the whole penis and it does seem to work better when I am standing, maybe
a possible leak, I am not sure. I started massaging a little bit below my balls, not much
but enough to feel it and that seems to help also. If you are going to massage below the
balls, get your partner involved, one above the balls and one below, works very well
for me and my wife enjoys feeling "her" cock get bigger and harder. Does not take very
long at all once my wife is involved and you will both enjoy it greatly. Good Luck!