Does bimix and PGE1(Alprostadil) have the risk of priapism as Trimix or its lower?

[Frenchie]

I want to try injections for my ED but here is the problem. I live in a small town in Europe and the only hospital in the city with ER is the hospital I work in so I sure as hell don't wanna go there if something bad happens. So thats why I want to avoid priapism at all costs. There is another hospital in the next city but I don't have a car so its not possible to go there if something goes wrong. What can I do to minimize the risk of priapism as low as possible? Would it be a good idea to tell the doctor to prescribe Phenylefrine?

[bldoink]

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[computerguy]

I am going to look into this. I was extremely cautious with trimix, but found that the lowest does that produces the desired result tends to last dangerously close to the 4 hour mark. I would never inject it without having the injectable antidote on hand, and twice I had to use it. Fortunately it worked immediately. Will post back if I get to trying bimix.

[computerguy]

Bumping this up, because this question was asked on another forum, and someone recommended asking here. I also read reports from a few other guys, who like me end up with a close to 4 hour erection with just small enough dose to do the job.

I am not sure if the concentrations are "standard" but I was on 20/30/1 and just switched to 10/30/1 (trimix #5 ?), but have not tried it yet. I am hoping that cutting the alprostadil in half will help. Does that sound reasonable? If indeed bimix has lower incidence of priapism then I'd think so?

[Sean762]

Bumping this up, because this question was asked on another forum, and someone recommended asking here. I also read reports from a few other guys, who like me end up with a close to 4 hour erection with just small enough dose to do the job.

I am not sure if the concentrations are "standard" but I was on 20/30/1 and just switched to 10/30/1 (trimix #5 ?), but have not tried it yet. I am hoping that cutting the alprostadil in half will help. Does that sound reasonable? If indeed bimix has lower incidence of priapism then I'd think so?

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

So Tri-Mix T-105 is found here for the breakdown of what the 30/1/10 means (I was wrong above which is why I struck through it):

30 mg Papaverine; 1 mg Phentolamine; 10 mcg Alprostadil/PGE-1 (keep in mind the last one is in MICROGRAMS).

https://www.rxbuyersclubusa.com/pricing

I'm attaching a screen shot of the breakdowns for folks to reference.


Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

[Sean762]

viewtopic.php?f=5&t=23914&p=227360#p227360

I updated the last post in the thread with the research I found. There's not a lot there about priapism (I was more focused on scarring/fibrosis caused by Papaverine)....but a couple of quotes said that Papaverine is more likely to cause priapism as well so the computerguy's doc reducing that component makes sense.

[computerguy]

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

Sean, thank you for the reply! I am looking at my new script, and it says: "30mg/ml Papaverine / 1mg/ml Phentolamine / 10 mcg/ml PGE1" so that sounds to me like it was the 20 of PGE1 cut to 10. Also from a medical study on dosages had "Each 1 cc of Trimix solution contains PGE1 at 10 ug/ml, papaverine at 30 mg/ml, and phentolamine at 1.0 mg/ml".

[Sean762]

Tri-mix T-105 is 10/30/1....but the ratio is not what you think. The 1 is a mcg (microgram) of Alprostadil....the main ingredient in the stack doing the work.

My understanding is the formulation is 1 mcg/ml.

Your 20/30/1 was 20mg (milligrams) of Papaverine, 30mg of Phentolamine, and 1mcg of Alprostadil....your new dose is listed the same way...so they cut the Papaverine down; not the Alprostadil.

Papaverine actually has a higher incidence of priapism than Alprostadil.....I did a long write up on this with Olympia Pharmacy...let me see if I can find it and link it.

Sean, thank you for the reply! I am looking at my new script, and it says: "30mg/ml Papaverine / 1mg/ml Phentolamine / 10 mcg/ml PGE1" so that sounds to me like it was the 20 of PGE1 cut to 10. Also from a medical study on dosages had "Each 1 cc of Trimix solution contains PGE1 at 10 ug/ml, papaverine at 30 mg/ml, and phentolamine at 1.0 mg/ml".

Well, I stand corrected. I had it completely backwards. Not sure what site I got that info from now....but clearly I was wrong. Apologies. I'll edit the post to correct the bad info.