Beginning Injections - - Frequency?

Sticking a needle Where? Courage, guidance and help.
Techman52
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Joined: Mon Aug 16, 2010 10:49 am
Location: Ballwin, MO 63021
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Beginning Injections - - Frequency?

Postby Techman52 » Thu Sep 09, 2010 1:12 pm

I have been prescribed bi-mix and today was my first self-injection under the urologist's supervision, the second in total. The first injection was 0.1ml which ony had the effect of relaxing and elongating my penis, with no true erection. This effect lasted a little over an hour. Today was 0.15ml and essentually the same results. My urologist told me not to inject more than once a week. He also stated the next injection (in a week) should be no more than 0.2 ml. [I am sure he is concerned about priapism.] I am aware of the concern with tissue scarring and using the precaution of alternating sides when injecting. The protocol he has me doing is to retract my foreskin, grasp the head and extend the penis as far as comfortable from the body, while holding extended, alcohol swab at the point where the penis joins the abdomen and inject at either the 3 o'clock or 6 o'clock position. The applying pressure at the injection site for 5 minutes to minimize bruising.

My question -- my urologist is insistant upon the once-a-week frequency, what, in general, is the groups frequency of injections? I currently am "arrow-straight" when erect and have on inherent signs of curvature which might be impacted by injection scarring.

Based on trial and error, how long has it take the fellow members to find the optimum doseage?

Sign me -- bummed out
Larry

Cajun Jeff
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Joined: Sat Aug 01, 2009 11:44 pm
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Re: Beginning Injections - - Frequency?

Postby Cajun Jeff » Thu Sep 09, 2010 2:48 pm

Not sure about BiMx but on Caverject I was told I could use it once every 24hrs. Dont I wish I would have use for it that often. :D

Cajun Jeff
68 years old, Married 48 years. Prostate Cancer surgery 11 years ago. Tried Pills, VED, moved to injections (EdEx) for past 6 years. Implanted with AMS 700 LGX by Dr Hellstrom in New Orleans at Tulane Medical. 1/13/20

Julios
Posts: 67
Joined: Thu Jun 24, 2010 6:28 pm

Re: Beginning Injections - - Frequency?

Postby Julios » Thu Sep 09, 2010 3:16 pm

Larry

My urologist, Randy Fagin, only limited me to one injection in 24 hours and no more than three per week. He started me at 0.1ml, but 0.08 seems to be enough.
Age 54
RP July 2010. All nerves spared on right, 25% on left
Pathology: T3b, Gleas 9, Pos Margins, EPE
Currently on ADT
Using Trimix successfully: 0.08ml; 20MCG Alprostadil 1MG Phentolamine 30MG/ML Papaverine

Techman52
Posts: 96
Joined: Mon Aug 16, 2010 10:49 am
Location: Ballwin, MO 63021
Contact:

Re: Beginning Injections - - Frequency?

Postby Techman52 » Wed Sep 15, 2010 4:02 pm

Well, week #3, third injection and at 0.2cc or 20 units of bi-mix. Minimal evidence of erection, more just like relaxed away from the body and hanging around. Next week we go for 25 units (0.25 cc ). It's really tempting to go up a full 10 units to 30.

Oh well - - -

Larry
Elevated PSA July 2009, Biopsy (postive) August 2009
Robotic surgery Sept 2009, Gleason 8-6, ED
VED, Cialis, Bi-mix unsuccessful
LGX Implant 11/22/11
Activation January 4, 2012

fiftiesmale
Posts: 1
Joined: Tue Sep 21, 2010 10:40 pm

Re: Beginning Injections - - Frequency?

Postby fiftiesmale » Wed Sep 22, 2010 1:00 pm

Hi all, I am new to this forum. My signature (if i filled it out properly) will show my history. I am currently trialing Bimix, and have some concerns. I am hoping that some of you can provide some feedback to assist me. thanks.

Specifically, I am concerned about how long it should take for the erection to decrease down to flaccid, or at least decrease down to the point where you do not have to consider going to the hospital.

I went to a (local) hospital with a priapism 4 hours after the first ‘test’ dosage (“.3”) that was administered (an hour away) at the Medical Center where i had my Prostatectomy DaVinci Surgery. It was not a fun experience, in the hospital. I was in the hospital for close to 4 hours. They first tried counter-injections to bring it down. They then did needle extraction to drain the blood. I was under a local, so I did not feel any pain, but there was discomfort, and it truly was traumatic.

I must really enjoy sex with my wife, because I have tried Bimix 3 or 4 more times (after I told myself that I would not use it again, after the priapism). I have tried the Bimix a total of 4 or 5 times.

First time, dosage was “.3” administered at the Medical Center (an hour away) where i had my Prostatectomy DaVinci Surgery (the ".3" is the standard amount that the Prostate Cancer administers to post Prostate Cancer Surgery patients who qualify for “injections”. Apparently it was way too much. By the time 4 hours came and went, I had not come down a bit. The nurse who administered it, examined me after an hour and was convinced that I was starting to come down (but that was not the case). I even took some of the Sudafed to assist (at the 2 hour mark, and again after 4.5 hours). I live over an hour away from the Medical Center, so I went to a local hospital. It has a great reputation, but it took them over an hour, close to 90 minutes, to start treating me after I had arrived there. To repeat, it was a nightmare situation, that i hope to never repeat.

After a phone call, two days later, the Medical Center concluded that the ".3" was too much for me. We scheduled a 2nd appointment for 2 weeks later, for a much smaller dosage.

Second time, dosage was “.1” administered again at the Medical Center (two weeks after the first attempt). This time, there was very little effect. The nurse asked me, and my answer was that I felt that I had achieved about 70% -75% erection in the office. Within an hour, things were totally down, and back to normal. The recommendation from the folks at the Medical Center was for me to increase to “.15 to .20” at home.

The third time, dosage was approx “.17”, at home. It was a great success. Good intercourse. However, as 4 hours approached, and things were not decreasing, I called the Medical Center . They were ready for me at the the Medical Center. I showered, got dressed, and figured “here I go again, another priapism, with the draining and everything”. However, short after 4 hours, things started to slowly go down. I actually started driving in the car (realizing it would take over an hour to get there). After about 20 minutes in the car, I realized that things were continuing to go down, so I made a U-turn, and headed back home. I was not totally flaccid until about 5-6 hours, but it did continue to decrease, until it became flaccid. I was greatly relieved.

The fourth time, dosage was about “.15”, at home. I achieved about a 90%-100% erection. Not as good as the .17, but usable. Once again, the erection continued longer that I had hoped. This time I did not call the Medical Center, but I continued to watch things. I actually did take a shower, and was ready to drive down to the Medical Center, just in case. It was around the 4 hour mark, that it slowly starting decreasing.

That was the last time. (about 2 weeks ago). We have only used Viagra since, as I debate my path forward.

So my primary questions relate to “the normal” or “the average” or maybe even the long end of “acceptable” erection duration?
Does anyone have an erection for about 4 hours? What is the duration of your erection, and how soon (after the injection) do you start to see things going down? I realize that it varies from guy to guy, but any numbers will help me get a feel for what others experience. Thanks.


Related information: My PSA was 6.2. My pre-surgery Gleason from biopsy was 4+3=7. The Robotic surgery was successful, the surgeon says he got it all, and saved both nerve bundles. There was some minor complications, due to prior surgery for hernia, and the surgeon had to take a path around the mesh that was put in during the hernia surgery. The post surgery biopsy was 4+3=7.

I have tried all the pills, and have had the best success with Viagra. I also purchased, and have used an Osbon Pump. With Viagra, the pump, and rings, I have had 90%-100% erection, but there is the “bend” point where the ring constricts things, down near the base of my penis. Dr Patrick Walsh’s book even addresses the issue of the bend – at the point of the ring constrictor.

I am not doing this for my wife, but she had some minor complaints about the bend point, and that it made it difficult for her to achieve the sensation, for her to achieve orgasm. I get as much satisfaction in pleasing her, to the point of orgasm, as I do in achieving orgasm myself. Therefore, her satisfaction is very important to me.

I have read about the success of Injections. I was excited to try the Injections. I was very pleased, and continue to be very pleased with the results of Injection. Truly, a couple of times, there was 100-105% percent erection, and my wife and I had the best sex since before surgery.

I am left in a point of confusion. What do I do now? My biggest concern and fear is having to go to the Hospital and go through the full drain experience again.

I think that if I knew with 110% certainty that I would always come down, around 4 hours (or preferably less) then I could continue with Injections (and without any worries).
However, each time, when I give myself a shot, in the back of my head, I wonder …. Will it go down? Or will I go to the Hospital.

I really wish that it would only last about 90-120 minutes (2 hours max). but I also do want the full 100% erection. So, though the 2nd time, with only “.1” brought things down in a much faster time frame, it was not really a usable erection.

I guess I will stop here, and see what your initial thoughts and recommendations are.
Age: 55; PSA 6.2; Biopsy: 1 of 10, Gleason 7 (3+4), Prostatectomy (DaVinci), PostOp: margins clear; post-op U/PSA: 0.04 (at 18 month); Viagra, and Osbon manual pump. Currently trialing Bimix (.3 is too much - had priapism; .10 too little)

Gingertom3
Posts: 83
Joined: Mon Aug 30, 2010 8:28 am
Location: England

Re: Beginning Injections - - Frequency?

Postby Gingertom3 » Thu Sep 23, 2010 6:59 am

Fiftiesmale, I can tell that you are very anxious about getting another priapism. And who wouldn't be? It's not just the pain, it's not just the intense embarrassment, it's also the danger of physical damage.
I don't know if the hospital gave you instructions on what to do about a priapism. You did the right thing by returning to the hospital. But did you try the other alternatives after 2 hours of priapism? In other words, did you attempt intercourse?
If not, did you try some other vigorous exercise or even masturbation? And if those didn't work, did you apply a cold compress like a bag of frozen stuff on your inner thigh? That's what I have been advised to do in case Muse goes wrong.
Thankfully the only side effect I've had is aching.
I hope you get better results from now on.

Jim

Julios
Posts: 67
Joined: Thu Jun 24, 2010 6:28 pm

Re: Beginning Injections - - Frequency?

Postby Julios » Thu Sep 23, 2010 3:40 pm

For the first time, I just had an erection that lasted 4 hrs last night. I changed syringes; from 1cc to 1/3cc. I assume there was enough imprecision in scales to result in me getting a much higher dose. With both syringes I was trying to take 0.08ml. I took two sudefed after two hours, then put ice on it after 3.5 hours. The ice seemed to help. Not a pleasant experience.
Age 54
RP July 2010. All nerves spared on right, 25% on left
Pathology: T3b, Gleas 9, Pos Margins, EPE
Currently on ADT
Using Trimix successfully: 0.08ml; 20MCG Alprostadil 1MG Phentolamine 30MG/ML Papaverine

Techman52
Posts: 96
Joined: Mon Aug 16, 2010 10:49 am
Location: Ballwin, MO 63021
Contact:

Re: Beginning Injections - - Frequency?

Postby Techman52 » Sat Sep 25, 2010 8:48 pm

Well, after much trial and error. I finally hit my stride and found the "magic" number: .35 cc or 35 units. Successful for a minimum of about 60 minutes then went to sleep like a good boy ;) . So next time we try that and check for repeatability.

Sign me -- not so bummed !!
Larry


Based on trial and error, how long has it take the fellow members to find the optimum doseage?

Sign me -- bummed out
Larry[/quote]
Elevated PSA July 2009, Biopsy (postive) August 2009
Robotic surgery Sept 2009, Gleason 8-6, ED
VED, Cialis, Bi-mix unsuccessful
LGX Implant 11/22/11
Activation January 4, 2012

Julios
Posts: 67
Joined: Thu Jun 24, 2010 6:28 pm

Re: Beginning Injections - - Frequency?

Postby Julios » Mon Sep 27, 2010 10:39 am

It took me 4 tries; just over a week. Had to start over when I changed syringes.
Age 54
RP July 2010. All nerves spared on right, 25% on left
Pathology: T3b, Gleas 9, Pos Margins, EPE
Currently on ADT
Using Trimix successfully: 0.08ml; 20MCG Alprostadil 1MG Phentolamine 30MG/ML Papaverine


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