How often do you inject?

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dxchase70
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How often do you inject?

Postby dxchase70 » Fri Jul 30, 2021 6:41 am

Hi all,

Just recently started with Trimix injections and so far it has been somewhat successful. I was wondering how often do you guys inject? I am especially interested in hearing from long time users. I've read that you should only inject 3 times a week and that you should do it every other day. I assume this is to avoid scarring? Has anyone injected twice within a 24 hour period? Say you had sex in the afternoon and then wanted to do it again the same night.

Also I have the following mix: Prostaglandin E1 5.88ug/ml, Papaverine HCl 18mg/ml, Phentolamine Mesylate 0.6mg/ml

Is that considered a weak mix? I injected 15 units and it gave me hard on for about 45 mins or so. Whereas Edex 20mcg gave me about a 2hr erection.
51 yo in NYC. Viagra no longer reliable after 15 years of use. I have just started trying Trimix injections (July 2021). Papaverine: 18mg, Phentolamine: 0.6mg, Prostaglandin: 5.88ug

ftwabeck3533
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Re: How often do you inject?

Postby ftwabeck3533 » Fri Jul 30, 2021 7:57 am

dxchase70 wrote:Also I have the following mix: Prostaglandin E1 5.88ug/ml, Papaverine HCl 18mg/ml, Phentolamine Mesylate 0.6mg/ml

Is that considered a weak mix? I injected 15 units and it gave me hard on for about 45 mins or so. Whereas Edex 20mcg gave me about a 2hr erection.


I have never injected twice in one day, but it would not concern me to do so. I have have injected Trimix approximately twice per week since June 2019, without scarring or other side effects. Getting the "cold storage" technique perfected is an on-going challenge.

I'll let you compare our two formulas (see below), the ratio and components are not the same.
Born 1955, Erectile Dysfunction, Robotic Prostatectomy (Oct 2018, Dr Bugg @ UCA, Birmingham, AL), PSA<0.007, Trimix User (30 mg Papaverine HCL, 1 mg Phentolamine MES, 10 mcg Alprostadil per 1 ML. My dose is 0.16 ML)

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bldoink
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Re: How often do you inject?

Postby bldoink » Fri Jul 30, 2021 11:05 am

dxchase70 wrote:....I was wondering how often do you guys inject? I am especially interested in hearing from long time users. I've read that you should only inject 3 times a week and that you should do it every other day. I assume this is to avoid scarring? Has anyone injected twice within a 24 hour period? Say you had sex in the afternoon and then wanted to do it again the same night.

I generally inject about 2 to 3 times a week but occasionally more. Think vacations.

I've been injection for 10 years without issues.

I'm unsure on the reason for the suggested weekly limit.

Yes I've injected twice in one day. It's not a normal practice. Think vacations again. For me it was a morning night thing so a little farther separated than afternoon/night.

dxchase70 wrote:Also I have the following mix: Prostaglandin E1 5.88ug/ml, Papaverine HCl 18mg/ml, Phentolamine Mesylate 0.6mg/ml

Is that considered a weak mix? I injected 15 units and it gave me hard on for about 45 mins or so. Whereas Edex 20mcg gave me about a 2hr erection.

Yeah that sounds like a weak mix to me. If you were using a full Edex 20 then your new mix has less than a third of the Alprostadil (Prostaglandin E1) of your Edex. The alprostadil is the most potent ingredient.

Was the alprostadil causing you problems? I also started on Edex 20s. I had to change as my insurance quit covering them. I switched to a locally compounded mono-mix of straight alprostadil (Prostaglandin E1) and saline at 80mcg per ml with a normal dose of 14 units.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 10+ yrs. It works. Treasure coast of FL.

dxchase70
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Joined: Thu Jun 17, 2021 11:25 am

Re: How often do you inject?

Postby dxchase70 » Fri Jul 30, 2021 11:41 am

Thanks for the responses guys.

First time I tried Edex, it was a 10mcg cartridge and it gave me a painful erection. However, the next few tries it was a bit more tolerable. The last one was 20mcg and it really worked out great. But like you, my insurance doesn't cover Edex so I am on Trimix now. I had a feeling it was a weak mix since the 15 units only gave me about 30-45 minute erection. Ideally I would like to go for about 2hrs. I guess I will I try 20 units next time.

So is there a reason why you chose monomix over trimix? What are the main differences between the 2?
51 yo in NYC. Viagra no longer reliable after 15 years of use. I have just started trying Trimix injections (July 2021). Papaverine: 18mg, Phentolamine: 0.6mg, Prostaglandin: 5.88ug

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bldoink
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Re: How often do you inject?

Postby bldoink » Fri Jul 30, 2021 12:43 pm

dxchase70 wrote:So is there a reason why you chose monomix over trimix? What are the main differences between the 2?

The Edex worked well and I figured why mess with success. So I had the doctor write a script for the same thing but stronger so I could inject a smaller volume. I used my Primary Care Provider as my Uro, who had prescribed the Edex, had just retired and I hadn't found a replacement yet.

I didn't want to add more drugs than necessary and the alprostadil worked just fine for me.

The research I'd read indicated that while all injection meds have some risk the alprostadil has the least risk.

The mono-mix in the form of Edex and Caverject are the only FDA approved injection drugs for ED. I'm uncertain if that's still the case but I think it is.

I had no difficulty finding a local (somewhat at about 35 miles) compounding pharmacy that could supply my mono-mix at what to me was a very reasonable price.

The same compounding pharmacy can supply tri-mix at the same cost but why would I want to go there. My mono-mix works just fine. I've never actually tried tri-mix.

The tri-mix contains the two additional ingredients along with the Alprostadil (Prostaglandin E1), the Papaverine and Phentolamine. Some guys may need the extra ingredients to achieve good erections. The addition of the two other drugs allow the use of less alprostadil which is helpful for those guys that never adapt to alprostadil and suffer intolerable pain from it. Some guys that are really sensitive to alprostadil and can't tolerate it at all have to use bi-mix that doesn't contain any alprostadil. The combination of drugs may have a synergistic effect where the combined effect of the drugs is greater than the sum of their separate effects (3 + 3 + 3 = 15 e.g.).

Good luck.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 10+ yrs. It works. Treasure coast of FL.

dxchase70
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Joined: Thu Jun 17, 2021 11:25 am

Re: How often do you inject?

Postby dxchase70 » Fri Jul 30, 2021 1:16 pm

I wonder why did my uro offer me Trimix instead of mono when I mentioned that Edex was working well. As I understand it, the other ingredients in Trimix is what causes the possible scarring? Seems like I should really go for monomix then. Damn, I should've checked on here first. lol
51 yo in NYC. Viagra no longer reliable after 15 years of use. I have just started trying Trimix injections (July 2021). Papaverine: 18mg, Phentolamine: 0.6mg, Prostaglandin: 5.88ug

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bldoink
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Re: How often do you inject?

Postby bldoink » Fri Jul 30, 2021 1:26 pm

It's easier to find a compounding pharmacy that does tri-mix than it is ones also doing a mono-mix. Tri-mix is the money maker and many compounders get in essentially pre-mixed drugs they resell. Some sell the heck out of tri-mix and just don't want to be bothered with mono-mix. My compounder will make whatever the doctor prescribes. You can probably find a compounder in your general area that will make whatever the prescription orders. Unfortunately my compounder only ships within Florida.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 10+ yrs. It works. Treasure coast of FL.

dxchase70
Posts: 75
Joined: Thu Jun 17, 2021 11:25 am

Re: How often do you inject?

Postby dxchase70 » Fri Jul 30, 2021 1:36 pm

I looked up the compounding pharmacy that provided me with the trimix online. It's some place located in NJ. At their website, the have this listed:

Prostaglandin E1 Injection Solution 20ug, 40ug

This would be monomix?
51 yo in NYC. Viagra no longer reliable after 15 years of use. I have just started trying Trimix injections (July 2021). Papaverine: 18mg, Phentolamine: 0.6mg, Prostaglandin: 5.88ug

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bldoink
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Re: How often do you inject?

Postby bldoink » Fri Jul 30, 2021 2:20 pm

I've been getting a bit long winded without my usual disclaimer. Bear in mind that I don't know shit!

Anything I post is at best based on my own experiences. At worst it's based on hallucinations and or delusions (Don't forget I'm a child of the 60s). Internet forum advice is likely worth what you paid for it, or worse. Always ask your doctor and follow his/her advice.
----------------------------------
Sounds like it. But it also sounds like they're trying to duplicate the Edex exactly except, I assume without the proprietary cartridge system. I like the version I get that allows me to inject way less that a whole ml.

I don't know where you are (NJ?), but if you're interested in a mono-mix you could try calling some compounding pharmacies and ask if they can make a mono-mix to order. Most compounders won't be certified to make sterile injection drugs but they should at least be able to point you towards those that are certified for that. Of course the first call would be to your current pharmacy to ask them if they're capable of mixing to order or are they limited to those two listed mixes.

My mix is 80mcg per ml but I plan to ask my current doctor to change it to 100mcg per ml just to make keeping track of my actual dose easier. Not that it's a big deal at all. At the 80mcg mix I have to use a calculator or break out pencil and paper. I'm math challenged. At 100mcg/ml I can easily figure that in my head. However, for just your own use you really don't need to keep tract of the exact mcg of alprostadil you're using. I just like to know.

Obviously if you only use a tiny amount, like a few guys, the strong mix is a bad idea. You need to have your mix weak enough so that you are using a dose volume large enough to accurately meter with your syringe. If you were using Edex 20s, as I was, then that shouldn't be a problem at 50, 80 or even 100mcg/ml.

Good luck.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 10+ yrs. It works. Treasure coast of FL.

dxchase70
Posts: 75
Joined: Thu Jun 17, 2021 11:25 am

Re: How often do you inject?

Postby dxchase70 » Fri Jul 30, 2021 2:56 pm

I am actually located in NYC. The compounding pharmacy where I received my trimix is in NJ. Anyway I will use up the trimix that I have now but I will definitely ask about monomix next time I'm at the doctor's office. Does seem like the way to go.

As always, thanks again for all the information. I appreciate the disclaimer but I do trust your opinion. You sound more knowledgeable than most people. :)
51 yo in NYC. Viagra no longer reliable after 15 years of use. I have just started trying Trimix injections (July 2021). Papaverine: 18mg, Phentolamine: 0.6mg, Prostaglandin: 5.88ug


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