How common is it for injection dose to stay the same or increase?

Sticking a needle Where? Courage, guidance and help.
GoodWood
Posts: 112
Joined: Sun Jun 16, 2019 1:07 pm

How common is it for injection dose to stay the same or increase?

Postby GoodWood » Wed Sep 04, 2019 4:21 pm

Hey guys,

How common is it for the “right dose” to stay the same verses increase over time.

I’m currently on 40units of a medium strength. I started on 20units of a mild strength a year and a half ago. My experience is that the dose has crept up steadily over time. What is your experience?
51yo. Progressively worsening ED over 6 years. No HTN, DM, or related health issues. 20-40mg of Sildenafil or TriMix (30mg, 4mg, 40mcg) 25units. Doses have been increasing so staying open to the idea of an implant. Pumping daily to maintain size.

bldoink
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Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: How common is it for injection dose to stay the same or increase?

Postby bldoink » Wed Sep 04, 2019 4:33 pm

I don't have a good answer. I'll speculate that it depends on the cause of your ED. I'm sure if your ED is due to a venous leak that is getting progressively worse you'll continue to need stronger doses until such point that it doesn't work even with a constriction ring.

In my case, as far as I know, I don't have venous leak issues. Mine appears to be caused by nerve damage from prostate removal. My dose remains fairly steady but does increase a bit as my mix ages. Hopefully that will remain the case.

So, I obviously have no idea what a general answer to your question would be. I'm guessing it depends on the cause of the ED.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 12 units. Originally Edex20, then compounded PGE-1 - cost. Inject. ~ 8 yrs. It works. Treasure coast of FL.

mattmdv
Posts: 60
Joined: Fri Aug 09, 2019 8:51 pm
Location: Ohio

Re: How common is it for injection dose to stay the same or increase?

Postby mattmdv » Wed Sep 04, 2019 4:34 pm

Sorry, I can't help, Haven't found that "Right Dose" yet.
62 Years old, married 40 years, no medical issues, (except ED), retired U.S. Army, 22 years, keep busy working P.T. for several funeral homes.

GoodWood
Posts: 112
Joined: Sun Jun 16, 2019 1:07 pm

Re: How common is it for injection dose to stay the same or increase?

Postby GoodWood » Wed Sep 04, 2019 6:16 pm

bldoink wrote:I don't have a good answer. I'll speculate that it depends on the cause of your ED. I'm sure if your ED is due to a venous leak that is getting progressively worse you'll continue to need stronger doses until such point that it doesn't work even with a constriction ring.

In my case, as far as I know, I don't have venous leak issues. Mine appears to be caused by nerve damage from prostate removal. My dose remains fairly steady but does increase a bit as my mix ages. Hopefully that will remain the case.

So, I obviously have no idea what a general answer to your question would be. I'm guessing it depends on the cause of the ED.


How long does it take for your mix to age to the point that it doesn’t work as well? I keep mine in the chiller box in the bottom of the fridge. And now it’s 2 and a half months old.
51yo. Progressively worsening ED over 6 years. No HTN, DM, or related health issues. 20-40mg of Sildenafil or TriMix (30mg, 4mg, 40mcg) 25units. Doses have been increasing so staying open to the idea of an implant. Pumping daily to maintain size.

bldoink
Posts: 1527
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: How common is it for injection dose to stay the same or increase?

Postby bldoink » Wed Sep 04, 2019 11:05 pm

Well I got a double batch last time because I had 2 refills on a script that was about to expire. So I got 20ml in 20 1ml vials. I keep all but one vial hard frozen in the back of my freezer. The vial I'm using I keep in the front of the freezer. I started out using 12 units. I'm now using 15 units. I could probably bump up another unit, maybe 2. My mix is over a year old.

I'm not going to suggest that using mix that old is a wise practice.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 12 units. Originally Edex20, then compounded PGE-1 - cost. Inject. ~ 8 yrs. It works. Treasure coast of FL.

Whodat
Posts: 16
Joined: Thu Aug 08, 2019 11:21 pm

Re: How common is it for injection dose to stay the same or increase?

Postby Whodat » Thu Sep 05, 2019 2:07 pm

Have reduced my dosage from 25 units to 20 units. Maybe it's because GF began working out at the gym ? However accidentally used old stuff which said to discard after 08/2017 and has been kept in fridge and it worked as good as new!
Age 78 good health. Radiation prostate 28 hits 2 years ago with 6 months of horrible ADT. Good recovery and ED no worse.
Can't tolerate oral drugs but 2 years of Alprostadil 40mcg/ml 25 units is a miracle for 4 1/2 hours. Young GF is happy!!

ftwabeck3533
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Joined: Sat Jun 22, 2019 3:21 pm
Location: South Alabama
Contact:

Re: How common is it for injection dose to stay the same or increase?

Postby ftwabeck3533 » Thu Sep 05, 2019 2:27 pm

I am on my second 5-ml vial of Trimix (first Rx was filled in May, second in August). I pre-loaded about 30 syringes with my 15 unit (0.15ml) dose and put them all in the freezer. I have noticed that the 15 units may be a little too much for me (erections now last about 1.5 hrs (30 minutes at 100% firm ... one hour to decrease to 50% firm). I believe my nerves are showing signs of healing now that I am 11 months post robotic prostatectomy. I may try pushing a couple of units out of the syringe prior to injection next time I use the Trimix (inject 12-13 units).

Another sign of nerve healing is my response to the sildenafil (generic Viagra). I take 20mg a day, for penile rehab. I tried the 100mg "challenge dose" in the past with no response. Recently I have achieved penetrable erection quality on 40mg. I don't want to jinx myself or get overly excited, but things seem to be improving from an ED perspective.

Finally. I bought the standard package of OTC Sudafed a couple days ago, for use as an antidote to long-lasting erections (Dr Mulhall's book recommends this treatment). Anyone using Sudafed for this purpose (priapism)? What's the dose and how did it work?
Born 1955, Erectile Dysfunction, Robotic Prostatectomy (Oct 2018, Dr Bugg @ UCA, Birmingham, AL), PSA<0.007, Trimix User (30 mg Papaverine HCL, 1 mg Phentolamine MES, 10 mcg Alprostadil per 1 ML. My dose is 0.15 ML)

bldoink
Posts: 1527
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: How common is it for injection dose to stay the same or increase?

Postby bldoink » Thu Sep 05, 2019 2:40 pm

I happy for you that your nerves seem to be healing. I pray you have continued improvement.

Sudafed use for that purpose is fairly common. I've used it for that purpose. I'm much better now days at determining the correct dose of juice so it hasn't been necessary in a very long time.
R.R.P 2011 Mayo Jacksonville, Dr. Michael Wehle. Nerve sparing - badly damaged. C in margin. V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 12 units. Originally Edex20, then compounded PGE-1 - cost. Inject. ~ 8 yrs. It works. Treasure coast of FL.

dtwarren1942
Posts: 1607
Joined: Wed Oct 27, 2010 7:58 pm
Location: Jersey Shore

Re: How common is it for injection dose to stay the same or increase?

Postby dtwarren1942 » Fri Sep 06, 2019 3:00 pm

I am a diabetic. When I first started, I worked up to 45 units before I got satisfactory results. However, over the succeeding three months I was able to reduce the effective dose to 15 units. I stayed at this level for about two years and then over the next six months, I had to slowly increase the dose until even 70 units could not generate satisfactory results. I stopped using Trimix over a year ago. I now depend on a VED.
Age 77
Diabetic
Pumping
Started Trimix injections 8/'11

Beachdude
Posts: 30
Joined: Mon Jul 08, 2019 12:19 pm

Re: How common is it for injection dose to stay the same or increase?

Postby Beachdude » Fri Sep 06, 2019 3:28 pm

I'm not on Trimix yet, but still on Edex. But my injection dose has been the same for years now. I have venous leakage, so I have to assume since the same dosage works for me now that the leakage hasn't gotten worse.
57
Edex injections in conjunction with Sidenafil. Use VED for conditioning.


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