Pentoxifylline during trimix therapy as a preventive measure against scarring

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Thisworld
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Joined: Sun Sep 06, 2020 3:01 pm

Pentoxifylline during trimix therapy as a preventive measure against scarring

Postby Thisworld » Tue Oct 14, 2025 9:35 pm

Pentoxifylline during trimix therapy as a preventive measure against scarring.
Has anyone ever heard of this?
Cuold this be a good strategy?
I want to hear your thoughts
Hard flaccid syndrome since 2019. Trying to get better with conservative treatments but an implant is on my radar

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AKJess
Posts: 79
Joined: Fri Sep 22, 2023 9:40 pm

Re: Pentoxifylline during trimix therapy as a preventive measure against scarring

Postby AKJess » Tue Oct 14, 2025 9:56 pm

Sounds legit. I use pentoxifylline along with cialis to treat PD; the purpose...cialis brings blood flow to help heal micro-tears due to traction therapy, and the pentoxifylline prevents the reformation of plaques and internal scarring.
56, married 33 years to an amazing woman, BPH, PD (47deg down to ~25deg), current Xiaflex treatment with Pentoxifylline & Cialis. Penile modeling with Restore X. Occasional ED triggered from pain response during intercourse.

CanGetItUpButNotOff
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Re: Pentoxifylline during trimix therapy as a preventive measure against scarring

Postby CanGetItUpButNotOff » Wed Oct 15, 2025 2:53 am

Is this an added ingredient to the TriMix cocktail? Or a separate treatment?
Born 1954. Diabetes, hypertension, atherosclerosis. Sildenafil iffy. Tri-Mix 30/3/20 Pap/Phen/PGE1 godsend pending long-term efficacy. Daily Cialis. Tried LiESWT 4 times, Botox, PT141, Eroxon, QST, DUS, Vertica, Ferticare, cabergoline, psycho+hypnotherapy

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AKJess
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Re: Pentoxifylline during trimix therapy as a preventive measure against scarring

Postby AKJess » Fri Oct 17, 2025 4:21 pm

CanGetItUpButNotOff wrote:Is this an added ingredient to the TriMix cocktail? Or a separate treatment?

Its an oral 400 mg tablet.
56, married 33 years to an amazing woman, BPH, PD (47deg down to ~25deg), current Xiaflex treatment with Pentoxifylline & Cialis. Penile modeling with Restore X. Occasional ED triggered from pain response during intercourse.

qcswral
Posts: 308
Joined: Sun Feb 10, 2013 8:01 pm
Location: Martin County FL

Re: Pentoxifylline during trimix therapy as a preventive measure against scarring

Postby qcswral » Sun Oct 26, 2025 6:20 am

Thisworld wrote:Pentoxifylline during trimix therapy as a preventive measure against scarring.
Has anyone ever heard of this?
Cuold this be a good strategy?
I want to hear your thoughts


Yes, when I first went on Trimix some 15 years ago within a year I had a hard pea size nodule form on the left side of my penis. It took a while but I managed to get into to see a Urologist who specialized in Peyronies disease. One of the meds he presccribed was Pentoxifyline 400mgs BID. Along with daily VED therapy, Vitamin E and the Pentox the nodule resolved over a 6 month period. The Urologist moved his practice out of my state, so I had to get a new doc, who knew nothing about Pentoxifylline given for ED, and as a treatment for scarring. I copied a medical article about Pentox given to men with ED and he has continued to prescribe for prevention of scarring and for ED. I am always amazed how little some physicians know about certain treatments in their so called field of expertise.
https://link.springer.com/article/10.10 ... 007-9255-1

This is one of many studies indicating a therapeutic value for Pentoxifylline prescribed for ED..
70 year old legally separated retired health-care professional. ED began in my early 50's. Viagra worked great for about 5 years, then had cardiac by-pass surgery and eventually moved to injections about 10 years ago.


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