PT-141 questions

Anything goes when it comes to ED.
GoodWood
Posts: 621
Joined: Sun Jun 16, 2019 1:07 pm

Re: PT-141 questions

Postby GoodWood » Tue Nov 15, 2022 2:42 pm

Disclaimer: I’m not a physician. Please talk with your doctor before trying any new medications or changing doses.


I’ve used PT141 a few times.

Subcutaneous injection.

The first thing I notice about 30-45 minutes later is a feeling of flushing, and feeling very slightly unwell. Sick is too strong a word. Just not feeling my best.

But my libido gets a boost from it after about an hour. The duration and intensity is dose dependent. My erections are improved with it but it wouldn’t be enough of an improvement for me to feel confident about penetrating sex without any other meds. I definitely feel much hornier. I continue to have nocturnal erections the night after taking a dose and wake with morning wood. That is a big change over my norm which is few nocturnal erections or morning wood.

The first few times I used it I tried different dosage levels. The syringes came from my urologist prefilled and they just described them as small, medium, and large. They didn’t tell me the exact dose (mg, or mcg). The high dose made me so horny I was selfish sexually, didn’t pay much attention to my partner. It was almost too intense. After we were done with sex I masturbated 5 or 6 more times during the next 18 hours. I woke up in the middle of the night grinding into the mattress. It was a bit much.

But the low and medium dose were better.

Since then I bought my PT141 from an online pharmacy. A 20mg vial. I don’t remember the price. Since then I’ve used 2mg at a time. (1mg, 2mg, and 4mg subcutaneous injection were the doses I found in literature). 2mg makes me horny. Improves my erection and I’ll want to have an orgasm 3 times in the next 18 hours. That seems more than enough.

I haven’t noticed any tanning or other side effects other than what I mentioned above about the flushing and feeling a little off. That feeling passes in about an hour as the horny feeling kicks in.

I don’t use it often, maybe once every month or two. I have no idea what the long term effects of using it frequently might be.

Talk with your doctor.
54yo, NYC. ED started at 40. 75 units BiMix + Atropine (Pap 30/Phen 6/Atr 0.2). Tri & QuadMix prostaglandins cause aching. Doses increasing. VED each morning to maintain size. Eager to talk about implant experiences.

dockuda
Posts: 7
Joined: Sun Mar 05, 2017 2:22 pm

Re: PT-141 questions

Postby dockuda » Tue Nov 15, 2022 9:13 pm

Please tell me what is PT141
ED since age 42. Currently on Trimix

GoodWood
Posts: 621
Joined: Sun Jun 16, 2019 1:07 pm

Re: PT-141 questions

Postby GoodWood » Tue Nov 15, 2022 10:07 pm

dockuda wrote:Please tell me what is PT141



PT-141 is a peptide that is known to act in the central nervous system to increase arousal.
54yo, NYC. ED started at 40. 75 units BiMix + Atropine (Pap 30/Phen 6/Atr 0.2). Tri & QuadMix prostaglandins cause aching. Doses increasing. VED each morning to maintain size. Eager to talk about implant experiences.

seekonk
Posts: 181
Joined: Thu Jul 22, 2021 10:33 am

Re: PT-141 questions

Postby seekonk » Wed Nov 16, 2022 11:48 am

GoodWood wrote:Disclaimer: I’m not a physician. Please talk with your doctor before trying any new medications or changing doses.


I’ve used PT141 a few times.

Subcutaneous injection.

The first thing I notice about 30-45 minutes later is a feeling of flushing, and feeling very slightly unwell. Sick is too strong a word. Just not feeling my best.

But my libido gets a boost from it after about an hour. The duration and intensity is dose dependent. My erections are improved with it but it wouldn’t be enough of an improvement for me to feel confident about penetrating sex without any other meds. I definitely feel much hornier. I continue to have nocturnal erections the night after taking a dose and wake with morning wood. That is a big change over my norm which is few nocturnal erections or morning wood.

The first few times I used it I tried different dosage levels. The syringes came from my urologist prefilled and they just described them as small, medium, and large. They didn’t tell me the exact dose (mg, or mcg). The high dose made me so horny I was selfish sexually, didn’t pay much attention to my partner. It was almost too intense. After we were done with sex I masturbated 5 or 6 more times during the next 18 hours. I woke up in the middle of the night grinding into the mattress. It was a bit much.

But the low and medium dose were better.

Since then I bought my PT141 from an online pharmacy. A 20mg vial. I don’t remember the price. Since then I’ve used 2mg at a time. (1mg, 2mg, and 4mg subcutaneous injection were the doses I found in literature). 2mg makes me horny. Improves my erection and I’ll want to have an orgasm 3 times in the next 18 hours. That seems more than enough.

I haven’t noticed any tanning or other side effects other than what I mentioned above about the flushing and feeling a little off. That feeling passes in about an hour as the horny feeling kicks in.

I don’t use it often, maybe once every month or two. I have no idea what the long term effects of using it frequently might be.

Talk with your doctor.


Do you get rebound ED afterwards?

Every time I’ve tried it I then couldn’t get any erection for at least a couple of weeks afterwards, maybe even longer. It’s like it burns out something and I’m not sure it’s reversible.

GoodWood
Posts: 621
Joined: Sun Jun 16, 2019 1:07 pm

Re: PT-141 questions

Postby GoodWood » Wed Nov 16, 2022 1:14 pm

seekonk wrote:]

Do you get rebound ED afterwards?

Every time I’ve tried it I then couldn’t get any erection for at least a couple of weeks afterwards, maybe even longer. It’s like it burns out something and I’m not sure it’s reversible.



No, I haven’t noticed that. I used it Sunday night. Got erections without any assistance, firm enough for masturbation twice, and a Trimix erection for sex once since then.
54yo, NYC. ED started at 40. 75 units BiMix + Atropine (Pap 30/Phen 6/Atr 0.2). Tri & QuadMix prostaglandins cause aching. Doses increasing. VED each morning to maintain size. Eager to talk about implant experiences.

PSSDorAmINormal
Posts: 481
Joined: Thu Jun 30, 2022 2:17 am
Location: Ohio

Re: PT-141 questions

Postby PSSDorAmINormal » Mon Nov 21, 2022 8:55 pm

Gadsiee wrote:
Captain1117 wrote:is it available as injection only ?


There is a nasal spray but most say it has 0 effect. Subcutaneous is the way to go

PSSDorAmINormal wrote:Does PT-141 also cause skin tanning?


I noticed a few new freckles, but it doesn't cause tanning like melanotan, it's designed not to have that effect


Any links or good information on preparing it or dosing?
SWM/never married. 39 years and not experienced. Injuries/trauma at young age due to lack of guidance and good sex ed. Low libido, loss of sensitivity/numbness. Possible PD and probable PSSD. No tests or doppler. Offered tadalafil, clomid and sildenafil

Gadsiee
Posts: 51
Joined: Fri Nov 12, 2021 3:33 am

Re: PT-141 questions

Postby Gadsiee » Tue Nov 22, 2022 6:01 am

GoodWood wrote:
seekonk wrote:]

Do you get rebound ED afterwards?

Every time I’ve tried it I then couldn’t get any erection for at least a couple of weeks afterwards, maybe even longer. It’s like it burns out something and I’m not sure it’s reversible.



No, I haven’t noticed that. I used it Sunday night. Got erections without any assistance, firm enough for masturbation twice, and a Trimix erection for sex once since then.


Me neither. The only thing i have noticed (but could be coincidence), is that when I use it more than once a week, it doesn't work as good.
25 years old. Lifelong (psychogenic?) ED. Can attain erections with viagra+cialis+PT141 but lose arousal randomly during sex with subsequent loss of erection.

Erections are like private jets. I don't have them

dtwarren1942
Posts: 1867
Joined: Wed Oct 27, 2010 7:58 pm
Location: Jersey Shore

Re: PT-141 questions

Postby dtwarren1942 » Thu Nov 24, 2022 11:42 am

PT 141 was originally used as a possible skin darkening agent for contractors being sent to work on projects close to the equator. Although it showed success for this use, the subjects of the trials also reported increased libedo.

In June, 2019, a form of PT 141 was approved by the FDA for increasing sexual desire in women; however, current research has not yet caught up to its use in men.
Age 80
Diabetic
Pumping
Started Trimix injections 8/'11

LuisFernandez
Posts: 407
Joined: Tue Jun 16, 2020 8:45 pm

Re: PT-141 questions

Postby LuisFernandez » Mon Dec 05, 2022 3:38 am

Do I need a prescription for this in the US? Would I be able to get it through a regular pharmacy?
Born 1986. ED. Peyronie's.
Considering an Implant. Consulting with Dr. Eid.
Using Cialis 10mg/day + 20mg for sex. Injections of PGE-1.
See my story: viewtopic.php?t=15016

LuisFernandez
Posts: 407
Joined: Tue Jun 16, 2020 8:45 pm

Re: PT-141 questions

Postby LuisFernandez » Mon Dec 05, 2022 3:47 am

Do I need a prescription for this in the US? Would I be able to get it through a regular pharmacy?
Born 1986. ED. Peyronie's.
Considering an Implant. Consulting with Dr. Eid.
Using Cialis 10mg/day + 20mg for sex. Injections of PGE-1.
See my story: viewtopic.php?t=15016


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