N-AcetylCysteine (NAC): Good or bad?

Anything goes when it comes to ED.

N-AcetylCysteine (NAC): Good or bad?

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tonyareias
Posts: 91
Joined: Tue Jan 04, 2022 10:26 pm

N-AcetylCysteine (NAC): Good or bad?

Postby tonyareias » Wed Jan 05, 2022 10:50 pm

I read about mixed results and opinions but for me 600mg 1h (as needed) before sex improve my erectile function.

Note: I have bad sexual (erection + delayed ejaculation) side effects (dose-dependent) when taking SSRI.

References:

N-acetylcysteine improves nitric oxide and α-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats


https://academic.oup.com/ajh/article/16/7/577/189404

In addition to increasing nitric oxide production, NAC can also potentiate the hemodynamic effects of nitric oxide by binding to it and forming a more stable substance, as evident from human studies where NAC treatment significantly enhanced endothelium-dependent vasodilation


https://www.sciencedirect.com/science/article/pii/S0085253815495870

NAC also helps to boost nitric oxide production, which can improve your blood flow and lower your heart attack risk. NAC may help to improve fertility in both men and women. One study found that men supplementing with both NAC and selenium experienced an increase in semen quality.


https://www.webmd.com/diet/health-benefits-nac

N-Acetylcysteine (NAC) inhibits renal nitrite and nitrate reabsorption in healthy subjects and in patients undergoing cardiac surgery


https://www.internationaljournalofcardiology.com/article/S0167-5273(14)01829-4/fulltext

N-acetylcysteine inhibits in vivo nitric oxide production by inducible nitric oxide synthase


https://pubmed.ncbi.nlm.nih.gov/11485373/

N-Acetylcysteine Negatively Modulates Nitric Oxide Production in Endotoxin-Treated Rats Through Inhibition of NF-κB Activation


https://www.liebertpub.com/doi/10.1089/152308602753625988

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