Botox Trials

Anything goes when it comes to ED.
johnsond1415
Posts: 18
Joined: Mon Jul 24, 2017 2:29 pm

Botox Trials

Postby johnsond1415 » Wed Mar 03, 2021 12:02 pm

Does anyone know whatever happened to the Botox study? They conducted a Phase I trial which showed a lot of success and were planning to do a Phase II study with more people, but I cannot find any mentions of that study online.

https://www.sciencedirect.com/science/a ... 2117300859
24 Years Old. Two unsuccessful venous ligation surgeries. Lifelong venous leakage.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: Botox Trials

Postby Markc2008 » Wed Mar 03, 2021 1:42 pm

I am also curious. I think it would help with flaccid shrinkage and ed from SSRI. I wander if you can have clinics do this?

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Botox Trials

Postby Simbarn » Thu Mar 04, 2021 4:16 pm

johnsond1415 wrote:Does anyone know whatever happened to the Botox study? They conducted a Phase I trial which showed a lot of success and were planning to do a Phase II study with more people, but I cannot find any mentions of that study online.

https://www.sciencedirect.com/science/a ... 2117300859

Is this the trial you are looking for?
https://clinicaltrials.gov/ct2/show/NCT03355963

https://www.smartpatients.com/trials/NCT03355963
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

johnsond1415
Posts: 18
Joined: Mon Jul 24, 2017 2:29 pm

Re: Botox Trials

Postby johnsond1415 » Thu Mar 04, 2021 10:48 pm

Think so but doesn’t seem like any results were posted. Wonder if that means something went wrong?
24 Years Old. Two unsuccessful venous ligation surgeries. Lifelong venous leakage.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Botox Trials

Postby Simbarn » Sat Mar 06, 2021 5:59 pm

johnsond1415 wrote:Think so but doesn’t seem like any results were posted. Wonder if that means something went wrong?


More time may be needed before results appear.
Here is another trial that is more recent and may be still in progress:
https://ichgcp.net/clinical-trials-registry/NCT04172558

It is being carried out by the same researcher, I note there is an email address for him in the above information. You could try contacting them for when results may be published. You might get a reply!
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

smphead
Posts: 459
Joined: Thu Aug 23, 2018 2:51 am

Re: Botox Trials

Postby smphead » Wed Apr 28, 2021 5:51 am

johnsond1415 wrote:Does anyone know whatever happened to the Botox study? They conducted a Phase I trial which showed a lot of success and were planning to do a Phase II study with more people, but I cannot find any mentions of that study online.

https://www.sciencedirect.com/science/a ... 2117300859


Already available:

https://centersforsexualmedicine.com/ma ... sfunction/
1978, male Netherlands. ED due Propecia use. Currently using cialis.
Thinking about Penile Implant.

User avatar
phallus
Posts: 39
Joined: Mon Jan 04, 2021 10:51 am

Re: Botox Trials

Postby phallus » Wed Apr 28, 2021 2:02 pm

smphead wrote:
johnsond1415 wrote:Does anyone know whatever happened to the Botox study? They conducted a Phase I trial which showed a lot of success and were planning to do a Phase II study with more people, but I cannot find any mentions of that study online.

https://www.sciencedirect.com/science/a ... 2117300859


Already available:

https://centersforsexualmedicine.com/ma ... sfunction/


Is this for real? Are they really offering botox for ED (off label) based on a couple of Phase I trials?

Anyone living in the US be willing to try this and report back? Could be the most effective and practical treatment for ED we'll ever have short of a cure like tissue engineering.
Born 1995
Possibly VL since 16.
Experimenting with PGE1 injections
which occasionally works too good and other times,
too poorly. Confusing situation.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Botox Trials

Postby Simbarn » Sat May 01, 2021 7:27 pm

smphead wrote:
johnsond1415 wrote:Does anyone know whatever happened to the Botox study? They conducted a Phase I trial which showed a lot of success and were planning to do a Phase II study with more people, but I cannot find any mentions of that study online.

https://www.sciencedirect.com/science/a ... 2117300859


Already available:

https://centersforsexualmedicine.com/ma ... sfunction/

This clinic is offering Botox for ED and the results of the recent trials do not seem to be available as yet?
I note they say it is not FDA approved and the studies have been small in number.
Therefore anyone partaking in this would essentially be a guinea pig!
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: Botox Trials

Postby Markc2008 » Sat May 01, 2021 10:56 pm

I may be going for this. I have been in contact with the clinic in Manhattan. Results from the trials have been good, but it is not approved by fda. I’m willing to give it a try before an implant.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Botox Trials

Postby Simbarn » Sun May 02, 2021 7:03 pm

Markc2008 wrote:I may be going for this. I have been in contact with the clinic in Manhattan. Results from the trials have been good, but it is not approved by fda. I’m willing to give it a try before an implant.

Do you have a copy of these results? Is this in relation to the latest trials?
If you are just about to get an implant, then I suppose you have nothing to lose with trying this.
Please do keep us informed of the whole process.
This treatment really does spark my interest as Botox causes muscle to relax. The penis does not contain the same muscle as our limbs do, however, it is comprised of a great deal of micro smooth muscle in all of the vascular erectile tissues. Botox affects this muscle in the same way.
This treatment may be very effective for some men.
However, there needs to be a sufficient amount of working smooth muscle in the erectile tissues for this treatment to work. So in the case of advanced fibrosis, which is the loss of smooth muscle and replacement with collagen, the effect may not be as good and CVOD will still occur, which is a venous leak.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.


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