My story and whether I should consider an implant

Anything goes when it comes to ED.
Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: My story and whether I should consider an implant

Postby Simbarn » Mon Jan 04, 2021 5:14 pm

Markc2008 wrote:Yeah I agree I should have probably reinstated the viibryd but I also don’t know if it is worth doing a year and a half later? My free T best I remember was 6. The ssri was used for premature ejaculation off label and anxiety. Yeah don’t know that helps now but that was the case. My protocol was 200mg/ml .24ml 3x a week and 350iu hcg three times a week with .125 anastrazole twice a week but I recently changed due to hair thinning and eliminated the hcg and anastrazole and lowered test dose to .20ml three times a week. I had some very slight libido improvement when starting that faded but I would say it seems to have improved erection quality some. Although since I’ve been on it a year now I have talked to the dr about coming off and seeing where I’m at naturally again. He wanted to simplify protocol first for a couple months and see how I felt and reacted. If this doesn’t help with everything I will be coming off and doing clomid for several weeks to restart natural production. But regardless before and on trt I’ve pretty much had the same issues from ssri. Still not in a good spot with function or desire.


I am also not sure what would happen if the AD was taken again at this time, but worth discussing with your doctor as something to try.
It is good that your doctor has suggested simplifying your TRT protocol. I do not like aromatase inhibitors. They are extremely difficult to control. If your E2 levels get too low they can take time to return and low E2 can make you feel like you are too.
Your T level may have been too high given the amount you were injecting per week, plus the T the HCG was creating. Your body will then convert too much into E2. Hence why the doctor then threw in an aromatase inhibitor.
Much better to lower the T dose which you have done.
I also think it would be a good idea to try and do a restart at your age. Two things about this that I know: They need to be run for a reasonable period (several weeks not being long enough) with a very slow taper off, the slow reduction is very important, otherwise the new level of T may not hold. Do not get concerned about the possible lack or worsening of sexual function whilst on Clomid as some men do not function well whilst on this drug.
This is due to the Zuclomiphene part of the medication. It can cause undesirable side effects. The Enclomiphene part of the drug is the one helping to give the pituitary a push to produce more gonadotropins. Clomid was designed for women not men.
The drug Androxal was designed for men, but did not get approval by the FDA due to political reasons. A massive shame.
It can also be a good idea to use HCG for a few weeks before the Clomid (without any exogenous T) to ensure the testes have returned to almost normal size and function, as they can be the slowest to respond once shut down for a period of time, when compared to the pituitary. HCG is quite effective at giving the testes a push back into action.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: My story and whether I should consider an implant

Postby Markc2008 » Tue Jan 05, 2021 7:30 am

Yeah I’m going to give six to eight weeks to this protocol and see where I’m at. If I’m not getting any better I’m going to start the process of getting off all of it. I do labs every two months so I’ve had a good idea of where everything is. I’ve had slightly high test at almost 1000 but estrogen,dht, all that has been within range. I wander if enclomiphene would be better?

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: My story and whether I should consider an implant

Postby Simbarn » Thu Jan 07, 2021 4:58 pm

Markc2008 wrote:Yeah I’m going to give six to eight weeks to this protocol and see where I’m at. If I’m not getting any better I’m going to start the process of getting off all of it. I do labs every two months so I’ve had a good idea of where everything is. I’ve had slightly high test at almost 1000 but estrogen,dht, all that has been within range. I wander if enclomiphene would be better?


Enclomiphene citrate would be far better than Clomiphene citrate. All the studies that Repros pharmaceticals did, showed how effective it was. Without the side effects that Zuclomiphene generates in Clomid.
The problem is where do you find a genuine high quality source of this? I have seen it on dubious sites in liquid form. Besides getting it analysed by a lab, you don't know if its the real drug.
I have been very tempted to try one of these research chemicals, but have not as yet.

A test level of 1000 is actually quite high. If your body sees that as excessive, there is some speculation that testosterone receptors may also begin to desensitise. A phenomena body builders know very well.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: My story and whether I should consider an implant

Postby Markc2008 » Thu Jan 07, 2021 5:24 pm

Yeah I’m in the process of letting my levels drop some. I have access to enclomiphene. My compounding pharmacy for my testosterone carries it and they are good. Defy Medical. So If I come off I’ll go with that then.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: My story and whether I should consider an implant

Postby Simbarn » Fri Jan 08, 2021 7:17 am

Markc2008 wrote:Yeah I’m in the process of letting my levels drop some. I have access to enclomiphene. My compounding pharmacy for my testosterone carries it and they are good. Defy Medical. So If I come off I’ll go with that then.

That is really good. I had no idea pharmacys in the US were compounding that. I'm in Australia, so don't think I'm that lucky. Would very much like to try it. Did you know Repros was trying to get it approved as an alternative form of HRT,for secondary hypogonadism?
That way all the hormones are still running.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: My story and whether I should consider an implant

Postby Markc2008 » Fri Jan 08, 2021 6:05 pm

Well good to know when I come off that’s a better option less likely to make sexual dysfunction worse. I really think something is out of whack from the antidepressants but just not sure what would keep me from returning to homeostasis after this long of being off.. it’s like arousal and sensation are gone.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: My story and whether I should consider an implant

Postby Simbarn » Sat Jan 09, 2021 5:08 pm

Markc2008 wrote:Well good to know when I come off that’s a better option less likely to make sexual dysfunction worse. I really think something is out of whack from the antidepressants but just not sure what would keep me from returning to homeostasis after this long of being off.. it’s like arousal and sensation are gone.

Have you read this read this review:
https://www.smr.jsexmed.org/article/S2050-0521(17)30072-0/pdf
You will need to copy and paste the link into a browser as I cannot get this link to save correctly in the post.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

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bldoink
Posts: 3719
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: My story and whether I should consider an implant

Postby bldoink » Sat Jan 09, 2021 5:55 pm

https://www.smr.jsexmed.org/article/S2050-0521(17)30072-0/pdf
You just have to surround your link with the forum code for a hot link as in:

Code: Select all

[url] desired hot link[/url]
You can also click on the code buttons at the top of your reply text box but then I have a hard time not inserting the text for the link in the wrong spot. It's easier to just type the code.

Some shorter and more simple links will often post as hot without the code but there's no guarantee so just use the code.

The actual publication linked is kind of depressing. I'd think any doctor still prescribing such drugs without a signed notice and waiver should be held liable.
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Nerve sparing - damaged. C in margin. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 12 yrs. It works. Treasure coast of FL.

Markc2008
Posts: 199
Joined: Fri Jul 31, 2020 10:45 am

Re: My story and whether I should consider an implant

Postby Markc2008 » Sat Jan 09, 2021 6:55 pm

Yeah I have seen this article before. I have for a while now thought I had pssd since I have most of these symptoms. The problem is no one know if this is permanent or just long lived or what. But how many years do you put up with this in hopes that it’s not permanent before you do something about it?

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: My story and whether I should consider an implant

Postby Simbarn » Sun Jan 10, 2021 7:12 pm

bldoink wrote:https://www.smr.jsexmed.org/article/S2050-0521(17)30072-0/pdf
You just have to surround your link with the forum code for a hot link as in:

Code: Select all

[url] desired hot link[/url]
You can also click on the code buttons at the top of your reply text box but then I have a hard time not inserting the text for the link in the wrong spot. It's easier to just type the code.

Some shorter and more simple links will often post as hot without the code but there's no guarantee so just use the code.

The actual publication linked is kind of depressing. I'd think any doctor still prescribing such drugs without a signed notice and waiver should be held liable.

Thanks for the help! It is concerning I do agree.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.


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