Apomorphine: my experience

Anything goes when it comes to ED.
Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Apomorphine: my experience

Postby Flavio » Fri Oct 23, 2020 5:34 am

Ok guys, I am really excited about this one.

I have just ordered a troche of apomorphine from The ED Clinic and the package is on its way.

I don't even know what a troche is but I'm feeling very optimistic. :D

According to the official website of The ED Clinic, apomorphine is a centrally acting drug that may help with the mental aspects of ED. Erections start in the brain and this treatment activates dopamine receptors (D2) to improve erections and libido. They specifically mention sexual performance anxiety but don't go into details.

I have tried apomorphine (Zyprima) in the past with excellent results and I have every reason to believe this one will be even better.

The ED Clinic only ships to the United States but if you live in Europe you can hire an American forwarder at http://www.parcl.com. I strongly recommend Yannick Libam, he's a brilliant American forwarder, he will take care of all the formalities and is already familiar with the product.

Tha package should arrive in a couple of days, I will keep you guys posted on my progress.
Last edited by Flavio on Sat Oct 24, 2020 3:27 pm, edited 1 time in total.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Simbarn
Posts: 239
Joined: Tue Mar 10, 2020 8:08 pm

Re: Apomorphine: my experience

Postby Simbarn » Sat Oct 24, 2020 8:34 am

I was doing some investigation into apomorphine and found this:
https://www.citizen.org/article/letter- ... ne-uprima/
It never got FDA approval in the US?
Age 56, ED issues for 10-15 years, on T replacement. Currently using generic Tadalafil 5mgs daily.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Sat Oct 24, 2020 8:51 am

Simbarn wrote:I was doing some investigation into apomorphine and found this:
https://www.citizen.org/article/letter- ... ne-uprima/
It never got FDA approval in the US?


Apomorphine for ED was never approved in the US but it was approved in Europe (brand name Uprima). It is currently being prescribed to treat other conditions, e.g. Parkinson's disease.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Sat Oct 24, 2020 3:31 pm

Simbarn wrote:I was doing some investigation into apomorphine and found this:
https://www.citizen.org/article/letter- ... ne-uprima/
It never got FDA approval in the US?


I've just read the letter and it's very entertaining.

I wonder if these 'citizens' are being sponsored by Pfizer or other big pharma companies. Apomorphine has a much better safety profile than Viagra and there is no reason why it shouldn't be widely available.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

whymenow
Posts: 22
Joined: Thu May 21, 2020 10:53 am

Re: Apomorphine: my experience

Postby whymenow » Sat Oct 24, 2020 4:12 pm

Keep us updated on this, Flavio.

Simbarn
Posts: 239
Joined: Tue Mar 10, 2020 8:08 pm

Re: Apomorphine: my experience

Postby Simbarn » Sat Oct 24, 2020 6:22 pm

This was a good read if you are interested in the history of Apomorphine:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995787/

It could help with psychogenic ED, possibly due its sedative properties by muting excessive sympathetic activity.
Interested to hear how effective these SL are for you, given your history with the above.
Age 56, ED issues for 10-15 years, on T replacement. Currently using generic Tadalafil 5mgs daily.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Sun Oct 25, 2020 3:51 pm

RUGIET was mentioned a few months ago on these forums and apparently they also sell sublingual apomorphine and papaverine, I wonder if anyone has more info on them.

Here's the original topic:

viewtopic.php?f=3&t=14494&p=127776#p127776
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Tue Oct 27, 2020 4:39 pm

A brief overview of apomorphine (brand name Uprima) for the treatment of ED:

https://www.youtube.com/watch?v=PzsyLWjzDI4
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Sun Nov 08, 2020 4:04 pm

Here's a not so positive info on apomorphine: according to this study, its half-life is only 2-3 hours. Correct me if I'm wrong, but this means the effect should last for a max of 5 hours, right? The half-life of Cialis is 17.5 hours, which allows for much more spontaneity.

https://www.docguide.com/apomorphine-pr ... sented-aua

My apomorphine tablets from theedclinic.com arrive tomorrow, expectations are high! I'll keep you guys posted on the results.
Last edited by Flavio on Sun Nov 08, 2020 4:18 pm, edited 2 times in total.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Flavio
Posts: 627
Joined: Wed May 19, 2010 4:56 am

Re: Apomorphine: my experience

Postby Flavio » Sun Nov 08, 2020 4:13 pm

Chosing the right drug is not enough, you have to know how to use properly. A study on the sequential use of apomorphine:

https://www.nature.com/articles/3900831
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.


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