does the fm57 clinical trial results appear vague to you?
It claims MED3000 being statistically significant in each separate cohort of severity (mild, moderate and severe) and it showed meaningful clinical difference in 60% of patients.
First of, what determines if your ED is mild, moderate or severe?
secondly, "meaningful clinical difference" -> does this mean the compound created an erection good enough for penetration? How many of the 60% success group had severe ED?
"It will likely find use in the substantial number of patients, especially those with ED of a mild to moderate nature" -> considering the 60% success rate (which is that of pills), this reads like people having good effect on pde5 inhibitors would be the ones mainly benefiting from MED3000 which appear to be rather few on frank talk. I find it difficult to believe MED3000 being able to help guys needing injections to perform.
I have only read these "results" on their web page, I cannot find the full published study of this as yet: https://clinicaltrials.gov/ct2/show/study/NCT03813992
I think this is the one they state using 1000 participants. So yes it does sound vague.
They determine the level of ED a participant has by using a particular questionnaire such as the IIEF; international index of erectile function. What they use is mentioned in the "methods" section in a published study.
Cant say much about the clinical difference until I see that published study. Same with the 60% success and severe ED. They do not mention this. You really need the full study to unravel much of that.
I think you are correct. It will do little for guys who are using injections. Injections are by far the most powerful method of inducing an erection because they directly stimulate smooth muscle to relax, they bypass everything!
This is the only study I could find:
https://www.sciencedirect.com/science/a ... 9517318520
Which is an earlier one with less participants.