MED3000 for ED: an update

Anything goes when it comes to ED.
Simbarn
Posts: 256
Joined: Tue Mar 10, 2020 8:08 pm

Re: MED3000 for ED: an update

Postby Simbarn » Mon May 31, 2021 7:05 pm

phallus wrote:@simbarn

does the fm57 clinical trial results appear vague to you?

It claims MED3000 being statistically significant in each separate cohort of severity (mild, moderate and severe) and it showed meaningful clinical difference in 60% of patients.

First of, what determines if your ED is mild, moderate or severe?

secondly, "meaningful clinical difference" -> does this mean the compound created an erection good enough for penetration? How many of the 60% success group had severe ED?

"It will likely find use in the substantial number of patients, especially those with ED of a mild to moderate nature" -> considering the 60% success rate (which is that of pills), this reads like people having good effect on pde5 inhibitors would be the ones mainly benefiting from MED3000 which appear to be rather few on frank talk. I find it difficult to believe MED3000 being able to help guys needing injections to perform.


I have only read these "results" on their web page, I cannot find the full published study of this as yet: https://clinicaltrials.gov/ct2/show/study/NCT03813992
I think this is the one they state using 1000 participants. So yes it does sound vague.

They determine the level of ED a participant has by using a particular questionnaire such as the IIEF; international index of erectile function. What they use is mentioned in the "methods" section in a published study.
Cant say much about the clinical difference until I see that published study. Same with the 60% success and severe ED. They do not mention this. You really need the full study to unravel much of that.
I think you are correct. It will do little for guys who are using injections. Injections are by far the most powerful method of inducing an erection because they directly stimulate smooth muscle to relax, they bypass everything!

This is the only study I could find:
https://www.sciencedirect.com/science/a ... 9517318520
Which is an earlier one with less participants.
Age 56, ED issues for 10-15 years, on T replacement. Currently using generic Tadalafil 5mgs daily.

whymenow
Posts: 27
Joined: Thu May 21, 2020 10:53 am

Re: MED3000 for ED: an update

Postby whymenow » Tue Jun 01, 2021 10:34 am

Vague or not! Fingers crossed! Anything new is welcome. I hope we can try MED3000 soon!

oldbeek
Posts: 1772
Joined: Sun Sep 10, 2017 1:46 pm
Location: Los Angeles area

Re: MED3000 for ED: an update

Postby oldbeek » Wed Jun 09, 2021 2:09 pm

If it would put feeling back into my glans, I would use it in combination with my implant. Now, occasionally the glans will engorge and get sensitive.
79, good health, RP 7-2017, all nerves taken , PSA 0.05, 4-18,, .08 11/18,.07 1/19,.05 4/19, .06 2/20 Pain with trimix, implant 4-18, Infra-pubic, AMS lgx 15 cm with 5cm rte. Implant at USC Keck. Dr Boyd and Dr Loh Doyle 6 x 4.5, 800 AUS 7-21-20

Flavio
Posts: 645
Joined: Wed May 19, 2010 4:56 am

Re: MED3000 for ED: an update

Postby Flavio » Thu Jun 10, 2021 2:33 pm

An interesting article on MED3000 and the ED market:

MED3000 doesn’t contain a drug so it is expected to have fewer side effects.

What’s even more impressive is that the route to medical device was carried out during a global pandemic, though James noted that the Zoom meetings may have perhaps sped up the process.

Being a medical device, the regulatory pathway ended up being much faster than it would have been with MED2005.

These developments have been cheered up by the market, with shares rocketing 240% in the year to date.


(MED3000 isn't even for sale yet and these guys are already making millions!)

https://www.proactiveinvestors.co.uk/co ... 46551.html
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Simbarn
Posts: 256
Joined: Tue Mar 10, 2020 8:08 pm

Re: MED3000 for ED: an update

Postby Simbarn » Thu Jun 10, 2021 7:25 pm

Thank you Flavio.
This is certainly getting interesting!
Age 56, ED issues for 10-15 years, on T replacement. Currently using generic Tadalafil 5mgs daily.

Flavio
Posts: 645
Joined: Wed May 19, 2010 4:56 am

Re: MED3000 for ED: an update

Postby Flavio » Mon Jun 14, 2021 3:32 pm

Latest news from Europe (April 2021):

https://www.youtube.com/watch?v=yoFCZwkbPYs
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

ventura
Posts: 81
Joined: Mon Oct 10, 2011 12:07 pm

Re: MED3000 for ED: an update

Postby ventura » Tue Jun 15, 2021 1:45 pm

Great news but unfortunately this drug will not work for most of us on this board. Those with Prostate removal. Unless I am reading wrong this drug will not work for most of us

tommyl1
Posts: 6
Joined: Sun Dec 01, 2019 7:53 am

Re: MED3000 for ED: an update

Postby tommyl1 » Tue Jun 15, 2021 9:19 pm

Sadly this concoction has been around since 2005.
I actually invested in Futura while the phase 3 trial was underway.
At that point it was called MED 2005 and contained the drug GTN.
It failed the trial giving the same results as the placebo.
If the stuff was effective Futura would have been bought out by a major drug company years ago.
As far as the interviews on Proactive they have a good line of BS ....I will give them that.

Flavio
Posts: 645
Joined: Wed May 19, 2010 4:56 am

Re: MED3000 for ED: an update

Postby Flavio » Tue Jul 13, 2021 10:46 am

UPDATE: MED3000 is now called EROXON. The new gel is mentioned on the popular online pharmacy Treated.com and should be available soon.

https://www.treated.com/erectile-dysfunction/eroxon
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

confused95
Posts: 76
Joined: Tue Mar 23, 2021 4:25 am

Re: MED3000 for ED: an update

Postby confused95 » Fri Jul 16, 2021 7:53 am

Flavio wrote:UPDATE: MED3000 is now called EROXON. The new gel is mentioned on the popular online pharmacy Treated.com and should be available soon.

https://www.treated.com/erectile-dysfunction/eroxon


Mate. Do you think it’ll work like PGE1? Thus independently from anxiety and sexual stimulation?
25yo from Italy. Psychogenic ed since dec 2019, got worse in Jan 2021 (can hardly masturbate but I still have some super hard morning woods and crazy spontaneous erections). On antidepressants now, working hard to get back to my heyday :(


Return to “General Discussion”

Who is online

Users browsing this forum: No registered users and 2 guests