Chinese patent: oral phentolamine for ED

Anything goes when it comes to ED.
Flavio
Posts: 890
Joined: Wed May 19, 2010 4:56 am

Chinese patent: oral phentolamine for ED

Postby Flavio » Fri Jun 19, 2020 4:18 am

I just came across this interesting document:

https://patents.google.com/patent/CN104013588A/en

The jargon is too technical and complicated for me, maybe some of the experts on FT could help us decipher this: who owns this patent, what exactly is a dispersible tablet, how can we get our hands on this treatment, etc.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Chinese patent: oral phentolamine for ED

Postby Simbarn » Mon Jun 29, 2020 4:17 am

Flavio wrote:I just came across this interesting document:

https://patents.google.com/patent/CN104013588A/en

The jargon is too technical and complicated for me, maybe some of the experts on FT could help us decipher this: who owns this patent, what exactly is a dispersible tablet, how can we get our hands on this treatment, etc.


With regard to your PM Flavio, I have had a look at this and it is just a patent that someone has filed in China during 2014 for a new preparation of the drug you are already taking. Looks like a dissolving/dispersible tablet in the mouth, possibly for sublingual absorption. It was in broken english and parts of it made no sense.
As just a patent that means it has not been made yet, its just an idea. It may not work of course as it has not been put through any studies and trials.

Here is an interesting study on an oro-dispersible version of viagra, which changes its pharmacokinetics (absorbtion and metabolism of the drug) which may alter how side affects are felt:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808105/
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.

Flavio
Posts: 890
Joined: Wed May 19, 2010 4:56 am

Re: Chinese patent: oral phentolamine for ED

Postby Flavio » Mon Jun 29, 2020 4:16 pm

Simbarn wrote:
Flavio wrote: [...] Looks like a dissolving/dispersible tablet in the mouth, possibly for sublingual absorption. [...]


Thanks for you reply. Do you think sublingual tablets are more effective?
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Simbarn
Posts: 358
Joined: Tue Mar 10, 2020 8:08 pm

Re: Chinese patent: oral phentolamine for ED

Postby Simbarn » Mon Jun 29, 2020 7:06 pm

Flavio wrote:
Simbarn wrote:
Flavio wrote: [...] Looks like a dissolving/dispersible tablet in the mouth, possibly for sublingual absorption. [...]


Thanks for you reply. Do you think sublingual tablets are more effective?

I don't have any experience with them. Regarding the study I provided, it suggested it may change how side affects of the drug can be felt, by altering how quickly the drug is absorbed and metabolised in the body.
Age 57, ED issues for 15-20 years. Testosterone replacement with Enanthate and Ovidrel. Currently using generic Tadalafil 2.5mgs and Resveratrol daily.


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