Scouting report: checking in with my own limited experience thus far. Have dosed it twice. First was 1.0g @ night. Pretty much nothing. Second attempt was 2.0g @ night - did not feel appreciably horny / in heat. Nocturnal tumescence was decent and markedly better than recent experience (especially for a guy w/ ED). 5am / 8 hrs later I took 60mg sildenafil. I've found that sildenafil's effects are pretty short-lived but I would say I got an erection that was better than sildenafil alone (even compared to a full 100mg dose). But I didn't feel any extra horniness. I will say that in my zeal to get going with this my cautious ramp-up has been pretty quick.
My understanding is you want to have an empty stomach to minimize nausea, which I did. Regardless, I took an anti-nauseal compazine (10mg) 1/2 hr before injecting. I'm not sure it was necessary, at least for me.
My next attempt will be 2.5mg, and at some point I'll need to cut over to daily 5mg cialis and/or 20mg cialis / tadalafil to round out my testing. I really want this stuff to put me in absolute heat so that, in conjunction w/ the PDE5 nothing will stop this train. I'm willing to do the trifecta w/ trimix too but if not needed for now I'd prefer to keep that powder dry. But I probably WILL throw in arginine / citrulline and horny goat weed / maca combo pills. (Shock and awe my friends, shock and awe!)
I gotta find some suppliers to get this stuff cheaper, like the 10-vial boxes that Lance Hitchings mentions in this video
https://www.youtube.com/watch?v=rNWUsEV9-Uk which I recommend watching. I can find 10 and 100 vial boxes but the discount is "only" 50% on the 100 at one supplier.
EDIT, 4 Days Later: Trial #3> Took it to 30 units / 3mg (not 2.5 as planned above) around 7pm. No ED drugs in conjunction. Or a woman for that matter. Had frequent overnight wood, probably the strongest wood I recall having in years, even compared to what I got with a "test" shot of TriMix at an ED clinic. So I'm now convinced PT-141 does something significant for me. I'm not feeling some kind of primal urge to mate, to go hump a tree in the back yard if you will. I guess I can just eat a bunch of oysters when it matters.
But maybe I'll notice that something like a swimsuit print ad turns me on like a teenager. So I'm pleased that the drug does something (and seemingly well). I almost wonder why it's not getting airplay as a bona fide ED drug, even.
EDIT, 1 Week Later from Trial #3: Trial #4> Took 20+ units / 2+ mg. Took Cialis / tadalafil 5g daily for 5 days to allow the drug to phase in to max efficacy. This is a good combo. I might even dial back the PT-141 to like 15 units because while it wasn't priapism the wood has been frequent and strong, overnight and otherwise. I write this 12 hours after dosing the PT-141. I like this combo because I don't really need to take something right before game time, or during in the case of TriMix injections. PDE5 inhibitors are not enough for me; PT-141 is feeling like a godsend. It may be a while before I report on how it works in a live-fire exercise, but the troops are ready, standing at attention. You can't use PT-141 all the time (8x / mo max is what I've read) but I'll worry about that problem if and when it presents itself.
EDIT, a few weeks after Trial #4: I've been fortunate to start a new relationship. Two different experiences w/ 20mg Cialis & first 20 units of PT-141 and then yesterday 30 units of PT-141. The 20 units I felt needed a little more the 30 gave me too much erection throughout the night. I was never too concerned about priapism but 25 units might be the sweet spot; in theory if no wastage you could get 4 25 unit doses from a 10mg vial of the bremelanotide. The sex was great. For me this is a good combo, noting that you can't use PT-141 frequently.