PT-141 (Bremelanotide)

Anything goes when it comes to ED.
RDD1966
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Joined: Sun Dec 06, 2020 11:09 pm

Re: PT-141 (Bremelanotide)

Postby RDD1966 » Wed Mar 24, 2021 6:36 pm

Where can I get some of this to try ?

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Stew52
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Location: Central TX

Re: PT-141 (Bremelanotide)

Postby Stew52 » Thu Mar 25, 2021 6:02 pm

ETGuy71 wrote:Flavio, I haven’t noticed anything stimulate wise taking the sublingual PT141!
So I’m thinking your thought on the ability to cross the blood brain barrier is very like valid.
Is this the Everest product that is sublingual? I'd guess that MAY only be effective for PT-141 or Oxytocin which is a sublingual.
NOT an MD. 71, M51 yrs, CenTX US. Inj since 12/2016, a yr after pills stopped working. Caverject for a yr. 1/2018 Tri-Mix at 30 pap/2 phent/60 pge @0.3ml, now 0.5ml 80mcg/ml PGE1. DE/Anorgasmia setting in since 5/2019, worse now.

RDD1966
Posts: 2
Joined: Sun Dec 06, 2020 11:09 pm

Re: PT-141 (Bremelanotide)

Postby RDD1966 » Sat Mar 27, 2021 10:37 am

rich2222 wrote:
spooon wrote:
dtwarren1942 wrote:It is a research peptide so a doctor most likely will not prescribe. No guarantee of safety, but it is widely available online.


Can you point me to am online source etc? Appreciate it's at my risk.


Sent a PM

Could you also pm info, looked online too many to choose from. Want to make sure I'm not wasting money and time on fake site. Thanks for any help you got for me.

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Stew52
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Location: Central TX

Re: PT-141 (Bremelanotide)

Postby Stew52 » Wed Apr 14, 2021 6:26 pm

Had a 10mg in 10ml vial left from earlier testing so thought I'd give it a go again. Very similar results. Did 1.5mg at 10pm so the target sweet spot 6-12 hours later would kick in the following day. A moderate dose (for me anyway) targeted to produce a nice result but with moderate side effects. And it did. With a twist. I took a phenegren anti-emetic beforehand this time because, based on earlier experience, nausea a was bad. Within 10 min in a strong flushing and eyes burning, within 15miin pulse got heavy, which both subsided in 30-40 min, but only very very mild nausea this time. That's good. But had gas and bloating. Had an 80%+ erection much of the night off and on from 2'ish am. However the effects wore off by 9am (11 hrs) so we could not take advantage of the benefits. I'd have to do the shot at 4am to provide a benefit window at mid-day. However, today I feel like crap. Bad stomach, mild nausea and a level-4 headache. I will try again with a very early am shot and phenegren at 1.5mg to see if it helps the libido, reduces ED effects (lower trimiix dose), and helps with DE. But I am becoming increasingly of the mind that it's not for me with the unpleasant side effects.
NOT an MD. 71, M51 yrs, CenTX US. Inj since 12/2016, a yr after pills stopped working. Caverject for a yr. 1/2018 Tri-Mix at 30 pap/2 phent/60 pge @0.3ml, now 0.5ml 80mcg/ml PGE1. DE/Anorgasmia setting in since 5/2019, worse now.

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Stew52
Posts: 366
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

Re: PT-141 (Bremelanotide)

Postby Stew52 » Thu Jul 22, 2021 6:36 pm

Brief update. After a layoff for a while for no particular reason, I tried a PT141 dose last night to see how it affected injections. Results much like just above. Based on previous testing, I injected 1.5mg late at 1:15am during a pee break so the sweet spot would be the following mid-AM 8-12 hours out based on past testing effects. I started with a phenegren to keep down nausea and Afrin to abate the stuffiness. Still had flushing and a heavy heartbeat. Side effects were tolerable and back to sleep quickly. Had major nocturnal tumescence (boners) through the night. Awoke feeling "yucky", mild headache, moderately upset stomach and fatigued. And no horny feeling or boners all day. The mood-affecting and auto-boner sweet spot seemed to be sooner than before. In no mood for sex so injection aborted. Wife bummed. This stuff seems to work better when you are sleeping and is a bit of a deterrent to sex when awake with the side effects. So go figure. Your results may vary. I've got 6.5mg left to play with. I may try an early AM injection next. Good luck.
NOT an MD. 71, M51 yrs, CenTX US. Inj since 12/2016, a yr after pills stopped working. Caverject for a yr. 1/2018 Tri-Mix at 30 pap/2 phent/60 pge @0.3ml, now 0.5ml 80mcg/ml PGE1. DE/Anorgasmia setting in since 5/2019, worse now.

BrokenPiston
Posts: 155
Joined: Wed Oct 13, 2021 12:26 pm

Re: PT-141 (Bremelanotide)

Postby BrokenPiston » Sat Oct 16, 2021 2:02 am

You only live once. At my age I think I'm intellectually horny but maybe not primally, so what the heck let's give it a whirl.

I just ordered a 10mg vial of it. For all that I've read here and elsewhere I'm still not 100% clear how to take the vial and inject what dose. I know I should start low and then go higher. But it's still not clear step by step what I should do. I have experience injecting into my belly fat (6 mos of blood thinner years ago) so I'm over that hurdle. And I think the guidance is to use a 1/2" #30 needle.

But I need a detailed primer on what to do with the vial once I receive it.

EDIT: this video is perfect! I love how this product is gender neutral. https://www.youtube.com/watch?v=-RSEiLFc7Bc
ED since mid '20, with slight Peyronies. Thus begins a search for the right solution(s); 56yo a/o Sep '21. Three months into my quest (12/21), I think PT-141, Cialis/tadalafil 20mg and L-Arginine (maybe other herbs) are a winning formula. For now.

JohnSmith
Posts: 26
Joined: Wed Oct 07, 2015 9:32 am

Re: PT-141 (Bremelanotide)

Postby JohnSmith » Thu Oct 21, 2021 10:52 am

Word of caution to be careful with this (specifically combining it with other ED meds), I took it 6 years ago with cialis AND viagra. It caused some crazy painful erections that kept coming back, and then woke up with another painful one that was hard to get down (my dick was also a reddish/purple color that didn't look good), since then I've had ED problems.

Funnily enough I think I gained a bit of girth after that fateful night, I think that's how strong that combo was.

BrokenPiston
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Re: PT-141 (Bremelanotide)

Postby BrokenPiston » Thu Oct 21, 2021 6:17 pm

Absolute good advice there. I plan to first try it alone in a dose I almost expect to do nothing and then work up from there before even introducing PDE5 (there again ramping up PDE5 dosage).
ED since mid '20, with slight Peyronies. Thus begins a search for the right solution(s); 56yo a/o Sep '21. Three months into my quest (12/21), I think PT-141, Cialis/tadalafil 20mg and L-Arginine (maybe other herbs) are a winning formula. For now.

BrokenPiston
Posts: 155
Joined: Wed Oct 13, 2021 12:26 pm

Re: PT-141 (Bremelanotide)

Postby BrokenPiston » Sun Oct 24, 2021 3:14 pm

Scouting report: checking in with my own limited experience thus far. Have dosed it twice. First was 1.0g @ night. Pretty much nothing. Second attempt was 2.0g @ night - did not feel appreciably horny / in heat. Nocturnal tumescence was decent and markedly better than recent experience (especially for a guy w/ ED). 5am / 8 hrs later I took 60mg sildenafil. I've found that sildenafil's effects are pretty short-lived but I would say I got an erection that was better than sildenafil alone (even compared to a full 100mg dose). But I didn't feel any extra horniness. I will say that in my zeal to get going with this my cautious ramp-up has been pretty quick.

My understanding is you want to have an empty stomach to minimize nausea, which I did. Regardless, I took an anti-nauseal compazine (10mg) 1/2 hr before injecting. I'm not sure it was necessary, at least for me.

My next attempt will be 2.5mg, and at some point I'll need to cut over to daily 5mg cialis and/or 20mg cialis / tadalafil to round out my testing. I really want this stuff to put me in absolute heat so that, in conjunction w/ the PDE5 nothing will stop this train. I'm willing to do the trifecta w/ trimix too but if not needed for now I'd prefer to keep that powder dry. But I probably WILL throw in arginine / citrulline and horny goat weed / maca combo pills. (Shock and awe my friends, shock and awe!)

I gotta find some suppliers to get this stuff cheaper, like the 10-vial boxes that Lance Hitchings mentions in this video https://www.youtube.com/watch?v=rNWUsEV9-Uk which I recommend watching. I can find 10 and 100 vial boxes but the discount is "only" 50% on the 100 at one supplier.

EDIT, 4 Days Later: Trial #3> Took it to 30 units / 3mg (not 2.5 as planned above) around 7pm. No ED drugs in conjunction. Or a woman for that matter. Had frequent overnight wood, probably the strongest wood I recall having in years, even compared to what I got with a "test" shot of TriMix at an ED clinic. So I'm now convinced PT-141 does something significant for me. I'm not feeling some kind of primal urge to mate, to go hump a tree in the back yard if you will. I guess I can just eat a bunch of oysters when it matters. :) But maybe I'll notice that something like a swimsuit print ad turns me on like a teenager. So I'm pleased that the drug does something (and seemingly well). I almost wonder why it's not getting airplay as a bona fide ED drug, even.

EDIT, 1 Week Later from Trial #3: Trial #4> Took 20+ units / 2+ mg. Took Cialis / tadalafil 5g daily for 5 days to allow the drug to phase in to max efficacy. This is a good combo. I might even dial back the PT-141 to like 15 units because while it wasn't priapism the wood has been frequent and strong, overnight and otherwise. I write this 12 hours after dosing the PT-141. I like this combo because I don't really need to take something right before game time, or during in the case of TriMix injections. PDE5 inhibitors are not enough for me; PT-141 is feeling like a godsend. It may be a while before I report on how it works in a live-fire exercise, but the troops are ready, standing at attention. You can't use PT-141 all the time (8x / mo max is what I've read) but I'll worry about that problem if and when it presents itself.

EDIT, a few weeks after Trial #4: I've been fortunate to start a new relationship. Two different experiences w/ 20mg Cialis & first 20 units of PT-141 and then yesterday 30 units of PT-141. The 20 units I felt needed a little more the 30 gave me too much erection throughout the night. I was never too concerned about priapism but 25 units might be the sweet spot; in theory if no wastage you could get 4 25 unit doses from a 10mg vial of the bremelanotide. The sex was great. For me this is a good combo, noting that you can't use PT-141 frequently.
Last edited by BrokenPiston on Mon Dec 20, 2021 2:10 pm, edited 2 times in total.
ED since mid '20, with slight Peyronies. Thus begins a search for the right solution(s); 56yo a/o Sep '21. Three months into my quest (12/21), I think PT-141, Cialis/tadalafil 20mg and L-Arginine (maybe other herbs) are a winning formula. For now.

Phil65
Posts: 146
Joined: Sun Oct 28, 2018 2:25 pm

Re: PT-141 (Bremelanotide)

Postby Phil65 » Wed Nov 03, 2021 2:53 am

BrokenPiston wrote:[b]EDIT, 4 Days Later: Trial #3> Took it to 30 units / 3mg (not 2.5 as planned above) around 7pm. No ED drugs in conjunction. Or a woman for that matter.


Same here with 2mg. It got me hard enough after 90 minutes that some manual manipulation could possibly lead to decent sex. I will try 3mg in a couple days but have you read anything about not going over 4mg?
TRIPLE P SUPERMIX (30-2-50)
Papaverine 30mg/ml - Phentalomine 2mg/ml - PGE1 50mcg/ml
(+ 0.15mg/ml Atropine)


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