WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Anything goes when it comes to ED.
notaes
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby notaes » Wed Feb 19, 2020 7:47 pm

I’ve never heard of it either! No one seems to know what your talking about. Does it really exist or is this a joke?
66 yr old male married 36 yrs use trimix four yrs, cilais and Viagra. trimix work well developed scarring on both sides had implant 1/9/2020 at UT Med Ctr, Knoxville, TN Dr. John Lacy.

Lost Sheep
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby Lost Sheep » Wed Feb 19, 2020 8:38 pm

Flavio wrote:I just googled misoprostol and apparently it is used to induce abortions.

Also reduce post-partum bleeding, protect stomach lining from ulcers (used for people sensitive to non-steroidal anti-inflammatories), make insertion of IUDs easier and a number of other uses. Erectile function is not listed among them.

There is real danger of birth defects when using misoprostol as an abortifacient. It is not very effective, but where abortions are outlawed, a black market thrives.

However, if it does help with E.D. it might be due to the same mechanism that reduces post-partum bleeding. That is, constricting veins, which might help with venous leakage. This is a pretty wild speculation on my part, though. It would be interesting to hear from the one guy who the O.P. named. But I am not holding my breath. Especially since it is too late for this to help me, even if it did work. Having an implant pretty much preempts any other solutions.
Lost Sheep
AMS LGX 18+3 Nov 6, 2017
Prostate Cancer 2023
READ OLD THREADS-ask better questions -better understand answers
Be part of your medical team
Document pre-op size-photos and written records
Pre-op VED therapy helps. Post-op is another matter

Mattbg7
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby Mattbg7 » Thu Feb 20, 2020 3:22 pm

I think this is coming from a study the evaluated the effects of this drug compared to Caverject. The study found that misoprostol relaxed muscles in penile tissue more effectively than caverject.

However this experiment was done on tissue in a lab from the tissue taken from men who were undergoing a penile implant. So to my knowledge, no test has been done to study this drugs effects on erections in live men or animals.

Sounds promising though. I’m willing to try it.

Robert66
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby Robert66 » Fri Feb 21, 2020 11:38 pm

I hear it works just like pge 1
edex and tri mix 45/1/27 26 units

KenJ1947
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Location: North Dallas

Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby KenJ1947 » Wed Jun 24, 2020 2:30 am

Sure about the spelling? A search turned up this: Misoprostol, sold under the brandname Cytotec among others, is a medication used to prevent and treat stomach ulcers, start labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus.Wikipedia?
Married 50+ years, 75, ED for 10 years.

Dr Mark Allen, Plano, TX. Surgery at Baylor, Scott and White Frisco, TX. AMS 700 CX MS, 24 cm + 2 cm RTEs x 2.4 cm tubes, 100 ml reservoir.

4 grandkids (son 25, daughter 23, son 21, daughter 7).

rosnekacj
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby rosnekacj » Fri Aug 12, 2022 5:04 pm

My research finds that Misoprostol (generic) is named Cytotec (brand) made by Pfizer. It a synthetic prostaglandin E1 agonist. It is available in 100 and 200 mcg tabs.
Apparently, Muse suppositories contain this product. Muse comes in suppositories of 125, 250, 500, and 1000 mcg.
Using Cytotec would be significantly cheaper than Muse.
One would have to figure out how to dissolve the tabs (would DMSO work?) and use a plastic syringe to inject the appropriate amount into the urethra.

Any thoughts on this?
88 yo
UroxatralForUrineFlow
ED dueToAging
TRT with5%creamBio-identical T 2X, T level 500-800
Sildenafil,E prostaglandinInjection,VacuumPump
17 cm (6 3/4 in)MeasuredByVacuumPump
Implanted3/8/21,Titan22cm
Lost 1/2"LengthAfterImplant
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Anonymous FT Member
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Joined: Thu Jun 30, 2022 2:17 am

Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby Anonymous FT Member » Fri Aug 12, 2022 11:41 pm

rosnekacj wrote:One would have to figure out how to dissolve the tabs (would DMSO work?) and use a plastic syringe to inject the appropriate amount into the urethra.

Any thoughts on this?


Wondering the same thing. I think it works, but I'm not sure. Also I don't have a good method for putting into the urethra. I felt irritation there, so I'm not sure if it is the substance causing irritation or the fact that I'm not accustomed to urethral play.

seekonk
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Joined: Thu Jul 22, 2021 10:33 am

Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby seekonk » Sat Aug 13, 2022 10:58 am

rosnekacj wrote:My research finds that Misoprostol (generic) is named Cytotec (brand) made by Pfizer. It a synthetic prostaglandin E1 agonist. It is available in 100 and 200 mcg tabs.
Apparently, Muse suppositories contain this product. Muse comes in suppositories of 125, 250, 500, and 1000 mcg.
Using Cytotec would be significantly cheaper than Muse.
One would have to figure out how to dissolve the tabs (would DMSO work?) and use a plastic syringe to inject the appropriate amount into the urethra.

Any thoughts on this?


I don't think MUSE contains misoprostol, just alprostadil. They are similar drugs though. Alprostadil is PGE1 and misoprostol is a PGE1 "analogue."

Since they are similar, they would probably have to deliver them the same way (injection or suppositories) to induce usable erections. After all, I presume taking alprostadil by mouth doesn't really work and/or is possibly dangerous otherwise why inject in the first place.

Anonymous FT Member
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Re: WHY ISN'T ANYONE TALKING ABOUT Misoprostol ??? WHAT THE HELL ???

Postby Anonymous FT Member » Sat Aug 13, 2022 1:57 pm

https://en.wikipedia.org/wiki/Prostaglandin_E1#Sexual_dysfunction:~:text=Vitaros.%5B9,into%20the%20urethra.

Why couldn't a person mix misoprostol the same way? Where could we get a suitable cream that would not irritate the urethra?


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