How Good is PT-141?

Anything goes when it comes to ED.
Jaypeep
Posts: 13
Joined: Sun Nov 24, 2019 4:39 pm

Re: How Good is PT-141?

Postby Jaypeep » Wed Feb 26, 2020 4:45 pm

I tried PT-141 for a few months. As others have said, it’s pretty easy to find somewhere to order it from on the web. It is harder to time than viagra. My best successes with it was to take it 4-5 hours before planned sexual activity, pop a viagra like normal; and be able to go multiple times over the course of a few hours.
Downside could be major nausea which sucked. Sometimes it was worse than other times. The other thing I noticed was diminishing returns after a while. I would have to take a break from it for a while.
Upside is that it makes you super horny. You just want sex. Paired with viagra, I would be sitting on the couch AFTER having sex and just get an extreme erection that was super sensitive and wouldn’t go down until I had sex again.
I also got the weird stretchy sensation others mentioned. Not bad, just odd. It made me constantly want to do these big stretches that often resulted in a brief quick body shiver. I also noticed that the day after, I would have a dull ache in my lower back.
Anyway, that’s my experience with it. Really fun sometimes; but occasionally not so fun.
49 year old gay male. ED for 20+ years. Diagnosed with VL. Recently switched from pills to Trimix.

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GoodWood
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Re: How Good is PT-141?

Postby GoodWood » Wed Jun 02, 2021 10:14 pm

I just got 3 sample doses from my urologist and am eager to give it a try.

Do you remember what dose you took?
57yo, NYC. ED started at 40. Pills, then shots for 10 years. 24cm Coloplast Titan XL w/classic pump by Dr Eid 3/25/2025. Will meet for show & tell.
Implant journal: [url] viewtopic.php?f=6&t=26225[/url]

Markc2008
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Joined: Fri Jul 31, 2020 10:45 am

Re: How Good is PT-141?

Postby Markc2008 » Wed Jun 23, 2021 9:11 pm

Let us know how it works for you . I just got some from where I get my trt supplies.

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GoodWood
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Re: How Good is PT-141?

Postby GoodWood » Wed Jun 23, 2021 11:28 pm

I’ve tried it once.

About 5 hours after I took it was when I had the planned sexual encounter. It briefly improved my erection (made it firmer) I THINK. Not sure.
It definitely made me hornier although my libido is already pretty strong so I’m not sure how useful that it. It made me so horny I was sort of a selfish lover for a bit. Really more intent on my pleasure than my partners.

No significant side effects to this first dose.

So, I’m not sure… I’m going to try it a couple more times and see where I end up with it.
57yo, NYC. ED started at 40. Pills, then shots for 10 years. 24cm Coloplast Titan XL w/classic pump by Dr Eid 3/25/2025. Will meet for show & tell.
Implant journal: [url] viewtopic.php?f=6&t=26225[/url]

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Robertbyday
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Joined: Sun Feb 15, 2026 2:04 am

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WillPower
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Joined: Wed Feb 04, 2026 7:48 pm

Re: How Good is PT-141?

Postby WillPower » Sun Mar 01, 2026 2:34 am

I got my first vial little over a week ago, Ive taken it 3 times.
I find it doing exactly what everyone else say's. Makes me horny on and off. Gives me spontaneous erections on and off (more on than off). Including night time. My erection is slightly more rigid with my band and without. No noticeable improvement with a tri-mix shot.

In general it seems to be doing what I hoped for. ie: A more stable erection, that I dont have to work so hard to keep, or get.

Side effects are very mild. No nausea, bit of a headache. I do get some chills. Not enough to stop using.

It's early yet though, so jury's still out. Ill keep you posted.

HeavyMetalFan
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Joined: Wed Oct 08, 2025 5:11 am

Re: How Good is PT-141?

Postby HeavyMetalFan » Sat Mar 21, 2026 11:25 am

Based on the literature, MT2 is slightly more effective at inducing pro-sexual effects than PT141, on a mg-per-mg basis. That doesn’t stop you from just taking more PT141, however.

The nausea is in part due to its appetite-suppressing effects, which itself is due in part to it slowing gastric emptying.

A lot of the nausea can therefore be avoided by taking MT2/PT141 on an empty stomach, and not eating afterwards.

If you’re injecting these drugs, they should be filtered during reconstitution, and refrigerated after reconstitution.

Budward
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Location: BC Canada

Re: How Good is PT-141?

Postby Budward » Sun Mar 22, 2026 3:27 pm

I have had a lot of experience with PT-141 and Melanotan 2 and just finished my first vial of Kisspeptin. PT-141 will make you horny as a madman but no guarantee on when the erections will arrive or be good for sex. I got very strong night wood but for guaranteed sex then you are better off with Trimix. Also like Melanotan 2 if you take too much you can get highly nauseated so I would start small and work up. These are not everyday drugs as if you use them to much you build up tolerance meaning you have to use more and thus at more risk of nausea.
I like Melanton 2 as it has the duel tanning and horny factor, and I like having a dark tan. However you can adjust dosage and frequency of useage to keep your tan at a preferred level. Again no guarantee on the erection, but it gets me very horny and again great night wood. I didn't find that PT 141 had much tanning property at all.
If you are going to inject Trimix use it the day after you use the above mentioned. Otherwise the risk of the longer than wanted erection can happen which is a risk.

Kisspeptin is new and I just finished my first vile I probably reconstituted with too much Bacteriostatic water. What it did for me is give me a more mild hornyness, but boy did my seaman increase and pure white as well. It is known for seaman production. I will post more after the next vile. It is well tolerated by the body so larger doses do not produce nausea which is a nice factor.


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