Are there any GOOD up and coming ED medications?

Anything goes when it comes to ED.
CanGetItUpButNotOff
Posts: 309
Joined: Mon Sep 20, 2021 1:34 pm

Re: Are there any GOOD up and coming ED medications?

Postby CanGetItUpButNotOff » Mon Jun 02, 2025 10:56 pm

ElbowRoom wrote:It's interesting that it's being tested specifically for post-prostatectomy ED only. I wonder if it has damaging effects on the prostate tissues.
It does say "…potential to address other forms of ED.”, so maybe it does have more generalized hope.
Born 1954. Diabetes, hypertension and atherosclerosis. Sildenafil is iffy. Tri-Mix (30/3/20 Pap/Phen/PGE1) a godsend pending long-term efficacy. Daily Cialis. Tried LiESWT, Botox, PT-141, Eroxon, QST, DUS, Vertica, cabergoline, psychotherapy+hypnotherapy.

Flavio
Posts: 926
Joined: Wed May 19, 2010 4:56 am

Re: Are there any GOOD up and coming ED medications?

Postby Flavio » Thu Jun 05, 2025 9:15 am

Never_Enough wrote: [...]
Lets face it, theres no GOOD option- they all come with fairly significant drawbacks.
[...]


I beg to differ. Oral drugs are very effective but you need to find the right one(s) for you. Seeing a doctor is essential.
Age 40. Psychogenic ED for over 20 years. Current regimen: Udenafil 200 mg, oral phentolamine mesylate 40 mg, Seredyn.

Never_Enough
Posts: 200
Joined: Fri Nov 24, 2023 7:54 am

Re: Are there any GOOD up and coming ED medications?

Postby Never_Enough » Mon Jun 16, 2025 4:36 am

Flavio wrote:
Never_Enough wrote: [...]
Lets face it, theres no GOOD option- they all come with fairly significant drawbacks.
[...]


I beg to differ. Oral drugs are very effective but you need to find the right one(s) for you. Seeing a doctor is essential.


I've tried them all , even avanafil.

Cialis is maintenance. It does barely anything, viagra is better as is avanafil, bit I still just lose the erection once my heads gone.

Veds ate hopeless too.

There's no ED pill that bypasses the mental side of ED, so I wouldn't say they are very effective. They are somewhat effective, but it's not as though they produce a rock hard erection that lasts. It's more a good erection that still goes up and down.
39 m UK

Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.

timduncan
Posts: 84
Joined: Wed Apr 06, 2022 12:31 pm

Re: Are there any GOOD up and coming ED medications?

Postby timduncan » Wed Jun 18, 2025 9:58 am

Never_Enough wrote:
Flavio wrote:
Never_Enough wrote: [...]
Lets face it, theres no GOOD option- they all come with fairly significant drawbacks.
[...]


I beg to differ. Oral drugs are very effective but you need to find the right one(s) for you. Seeing a doctor is essential.


I've tried them all , even avanafil.

Cialis is maintenance. It does barely anything, viagra is better as is avanafil, bit I still just lose the erection once my heads gone.

Veds ate hopeless too.

There's no ED pill that bypasses the mental side of ED, so I wouldn't say they are very effective. They are somewhat effective, but it's not as though they produce a rock hard erection that lasts. It's more a good erection that still goes up and down.

pt141 + electrostimulation a low insensity (no shockwase, just ems device+ anal probe)

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Kodixx
Posts: 375
Joined: Wed Jan 08, 2025 5:32 pm

Re: Are there any GOOD up and coming ED medications?

Postby Kodixx » Wed Jun 18, 2025 1:10 pm

FWIW, I've had good libido results with PT-141. I'm 4+ months post-op and am diving back into PT-141.

- Chuck
timduncan wrote:pt141 + electrostimulation a low insensity (no shockwase, just ems device+ anal probe)
Feb 2025 - 58 yo, 38 with greatest wife ever
AMS CX, Tenacio, Dr Broghammer (excellent) - pre-op L:7", post-op @ 5 mo L: 6.75" G: 5.5"
2 wks pain, cycling-sex-lifting @ 7 wks, only minor discomfort @ 10 wks, felt like 'new normal' @ 16 wks

timduncan
Posts: 84
Joined: Wed Apr 06, 2022 12:31 pm

Re: Are there any GOOD up and coming ED medications?

Postby timduncan » Thu Jun 26, 2025 12:23 pm

Kodixx wrote:FWIW, I've had good libido results with PT-141. I'm 4+ months post-op and am diving back into PT-141.

- Chuck
timduncan wrote:pt141 + electrostimulation a low insensity (no shockwase, just ems device+ anal probe)


pt141 is way better than any other on demand pill.
my only concern is not to develop tachyphylaxis from it, because i need it.
electrostimulation is also good for nerves

Never_Enough
Posts: 200
Joined: Fri Nov 24, 2023 7:54 am

Re: Are there any GOOD up and coming ED medications?

Postby Never_Enough » Mon Jun 30, 2025 7:36 pm

timduncan wrote:
Never_Enough wrote:
Flavio wrote:
I beg to differ. Oral drugs are very effective but you need to find the right one(s) for you. Seeing a doctor is essential.


I've tried them all , even avanafil.

Cialis is maintenance. It does barely anything, viagra is better as is avanafil, bit I still just lose the erection once my heads gone.

Veds ate hopeless too.

There's no ED pill that bypasses the mental side of ED, so I wouldn't say they are very effective. They are somewhat effective, but it's not as though they produce a rock hard erection that lasts. It's more a good erection that still goes up and down.

pt141 + electrostimulation a low insensity (no shockwase, just ems device+ anal probe)


How are you administerig the pt141? Isnt there an issue with high BP and this peptide though?
39 m UK

Psych ED since forever less problems being erect alone.
3 kids. Long term partner.
CPPS pudendal neuralgia and muscle tightness in late 2023 making ED worse.
Cialis no longer works. Sildenafil 100mg with diazepam works some of the time.

User avatar
Kodixx
Posts: 375
Joined: Wed Jan 08, 2025 5:32 pm

Re: Are there any GOOD up and coming ED medications?

Postby Kodixx » Tue Jul 01, 2025 12:26 pm

Never_Enough, I take it SubQ because orally did not work for me. I've had elevated BP for at least 20 years and PT-141 only has a mild and temporary effect on my BP. That said, you should definitely consult with your Dr and consider starting with small doses and work up to a full dose to test the effects on your BP as well as other side effects.

- Chuck
Never_Enough wrote:How are you administering the pt141? Isn't there an issue with high BP and this peptide though?
Feb 2025 - 58 yo, 38 with greatest wife ever
AMS CX, Tenacio, Dr Broghammer (excellent) - pre-op L:7", post-op @ 5 mo L: 6.75" G: 5.5"
2 wks pain, cycling-sex-lifting @ 7 wks, only minor discomfort @ 10 wks, felt like 'new normal' @ 16 wks

alans4570
Posts: 45
Joined: Tue Nov 21, 2023 4:57 pm
Location: Wisconsin

Re: Are there any GOOD up and coming ED medications?

Postby alans4570 » Tue Jul 01, 2025 3:58 pm

PT-141 is for low libido. It did nothing for me except turn my face red for approximately a half hour. Then I had some blood work done to check my testosterone. It was in the basement. So I started TRT and that did the trick. Now I'm horny all the time. I tried to get my wife started on it as well, but she had one doctor who told her it wasn't a good idea for her age, and that was the end of that.
Age 74 Implanted 01/02/2024, Dr.Clavell AMS LGX, Ed for almost 20yrs. Cialis tried caused vision loss, Trimix also caused vision problems. Married 36 years.


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