Intralesional collagenase injections (Xiaflex)

This is for the guys who experience an onset of curving or bending of their penis. PD is a frustrating condition which often creates significant emotional and mental distress. It overlaps several other sexual function conditions.
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Blippo
Posts: 23
Joined: Tue Jul 25, 2023 3:36 am

Intralesional collagenase injections (Xiaflex)

Postby Blippo » Wed Aug 02, 2023 12:54 pm

Anyone tried these? Do they work?

Would they also, or could they, work for non PD ED?
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bldoink
Posts: 3719
Joined: Mon Apr 03, 2017 12:58 am
Location: Fl.

Re: Intralesional collagenase injections (Xiaflex)

Postby bldoink » Wed Aug 02, 2023 1:06 pm

I've never tried them. From what I understand there is some risk involved. But more importantly they are just for PD related issues, well that and dupuytren's contracture (trigger finger).
R.R.P 2011 Mayo Jacksonville, Dr. M. Wehle. Nerve sparing - damaged. C in margin. Radiation 2023, V.E.D, Viagra and PGE-1 (80mcg/ml) injections @ ~ 14 units. Originally Edex20, then compounded PGE-1 - cost. Inject. 12 yrs. It works. Treasure coast of FL.
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Anonymous FT Member
Posts: 663
Joined: Thu Jun 30, 2022 2:17 am

Re: Intralesional collagenase injections (Xiaflex)

Postby Anonymous FT Member » Wed Aug 02, 2023 10:48 pm

Blippo wrote:Anyone tried these? Do they work?

Would they also, or could they, work for non PD ED?


Never tried it because no doctor has ever confirmed whether or not I need such a thing. However what worries me a little is the warning that you can get breakage or snap something after the Xiaflex injection. What I would be interested in knowing is this a temporary thing, or does the fragility persist the rest of one's life?
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AKJess
Posts: 60
Joined: Fri Sep 22, 2023 9:40 pm

Re: Intralesional collagenase injections (Xiaflex)

Postby AKJess » Thu Oct 05, 2023 11:25 pm

Blippo wrote:Anyone tried these? Do they work?

Would they also, or could they, work for non PD ED?

I am on the second cycle of xiaflex. So far there is some improvement -- it is a pain in the ass not being able to do anything with your dick for a month after the injections though...especially when you have a needing partner. There is some discomfort involved, but nothing to serious -- you really need to keep up with the penis modeling.
55, married 31 years to an amazing woman, BPH, PD (47deg down to 35), current Xiaflex treatment with Pentoxifylline & Cialis. Penile modeling with Restore X. Occasional ED triggered from pain response during intercourse.
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