PT-141 for DE??

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Stew52
Posts: 266
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

PT-141 for DE??

Postby Stew52 » Mon Nov 02, 2020 8:55 pm

Saw several posts here and in other folders on PT-141 peptide, Bremelanotide. Perused about 20 YouTubes. Now apparently FDA approved for female libido enhancement which portends well for safety. Seem to be fair results for ED.

Has anyone here used it to treat or improve DE/Anorgasmia?

Uro endorsed trying it today though he had no experience with it. He does use it for female treatment. Oxytocin alone did nothing for me after 10 troches. Based on outcomes, he then suggested adding Cabergloline and then Wellbutrin. He felt that DE treatment was trial and error.

If some combo of that did not work, he then suggested adding "Cyproheptadine". I've not seen that mentioned here.
NOT an MD. 68, M48 yrs, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr. 1/18 Tri-Mix at 30 pap/2 phent/40 pge @0.3ml supp w/0.1-0.2ml 60mcg/ml PGE1 on occasion for a longer session. DE/Anorgasmia setting in since 5/19

Stew52
Posts: 266
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

Re: PT-141 for DE??

Postby Stew52 » Fri Nov 06, 2020 9:14 am

First dose here: viewtopic.php?f=3&t=14728&start=10#p140398 It will take a while to ramp up to an efficacious dose. Will keep you posted.
NOT an MD. 68, M48 yrs, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr. 1/18 Tri-Mix at 30 pap/2 phent/40 pge @0.3ml supp w/0.1-0.2ml 60mcg/ml PGE1 on occasion for a longer session. DE/Anorgasmia setting in since 5/19

Flavio
Posts: 396
Joined: Wed May 19, 2010 4:56 am

Re: PT-141 for DE??

Postby Flavio » Sun Nov 08, 2020 4:28 pm

I'd love to try PT-141 for ED. If you know any online store that sells it, please send me a PM.

It's absurd that this is marketed only for women, it is uncontroversial that it also works for men.
Age 40. Psychogenic ED for over 20 years. Current regimen: Avanafil 200 mg, oral phentolamine mesylate 40 mg.

Jaypeep
Posts: 13
Joined: Sun Nov 24, 2019 4:39 pm

Re: PT-141 for DE??

Postby Jaypeep » Sun Nov 08, 2020 5:49 pm

I have tried PT-141 a number of times. It is effective in ramping up your libido. I would pair it with viagra and it was fairly effective.
There are some downsides and challenges with it though. I wasn’t doing a daily dose, just a larger dose before sex. The problem is that it takes 4-6 hours to kick in, so you have to really plan and the timing can vary. It also can make you extremely nauseous, which definitely doesn’t make you feel sexy. If you get past that, then you are good. It lasts for a good 12 hours or so once it kicks in and you will feel really horny.
The day after, you can have some achiness in your lower back. The other downside is that if you use it frequently, it seems to diminish in effect. If you take a break and then restart, it will be effective again. There can also be a rebound afterwards where it’s harder to get aroused.
I stopped using it because I found it to be more trouble than it was worth but I did have some good times with it.
49 year old gay male. ED for 20+ years. Diagnosed with VL. Recently switched from pills to Trimix.

teddls
Posts: 5
Joined: Fri Mar 30, 2012 5:33 pm

Re: PT-141 for DE??

Postby teddls » Sun Nov 08, 2020 7:21 pm

I had very serious side effects ... total body aches and joint pain. I'm no doctor; but, it appears ... at least, for me ... to kick off inflammation through out my body. Side effects began about 8 hours after I injected myself and lasted for 18-24 hours. Yes, it increases your libido and helped improve erection. However, the side effects are a deterrent to any further use, by me.

Stew52
Posts: 266
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

Re: PT-141 for DE??

Postby Stew52 » Tue Nov 10, 2020 7:21 pm

teddls wrote:I had very serious side effects ... total body aches and joint pain. I'm no doctor; but, it appears ... at least, for me ... to kick off inflammation through out my body. Side effects began about 8 hours after I injected myself and lasted for 18-24 hours. Yes, it increases your libido and helped improve erection. However, the side effects are a deterrent to any further use, by me.


What doses did you guys do? At 2x0.5mg and 2x0.75mg I am getting mild/moderate side effects* but seemingly little benefit. More info later as I continue to increase dose (every other day). Some of the side effects have lessened with use.

* mild indigestion/gas-gurgling/acid( not nausea), stuffy sinuses and nasal passages (hitting Afrin), burning eyes, some minor malaise and mild headache (abating), slight elevation in BP with heavy pulse, peaks in 10-30 min and subsides now in 1-2 hrs. First hit subsided in 5 1/2 hrs.
NOT an MD. 68, M48 yrs, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr. 1/18 Tri-Mix at 30 pap/2 phent/40 pge @0.3ml supp w/0.1-0.2ml 60mcg/ml PGE1 on occasion for a longer session. DE/Anorgasmia setting in since 5/19

Flavio
Posts: 396
Joined: Wed May 19, 2010 4:56 am

Re: PT-141 for DE??

Postby Flavio » Wed Nov 11, 2020 12:08 pm

If you guys want a centrally acting drug with virtually no side effects, I strongly recommend apomorphine from theedclinic.com. This is only a second-line treatment but it is very effective and safe. Check out my thread on apomorphine for more details.
Age 40. Psychogenic ED for over 20 years. Current regimen: Avanafil 200 mg, oral phentolamine mesylate 40 mg.

dtwarren1942
Posts: 1755
Joined: Wed Oct 27, 2010 7:58 pm
Location: Jersey Shore

Re: PT-141 for DE??

Postby dtwarren1942 » Wed Nov 11, 2020 4:10 pm

I used PT-141 about ten times several years ago. I definitely felt improved libido, but it did little if anything to improve my erection quality. Left me with improved desire, but no erection to take advantage of it. It also generated a strange overall feeling that lasted for about an hour.
Age 78
Diabetic
Pumping
Started Trimix injections 8/'11

Stew52
Posts: 266
Joined: Fri Apr 13, 2018 4:22 pm
Location: Central TX

Re: PT-141 for DE??

Postby Stew52 » Sat Nov 21, 2020 7:50 pm

I did an update on my PT141 use including to improve anorgasmia here: viewtopic.php?f=3&t=14728&p=141727#p141727
NOT an MD. 68, M48 yrs, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr. 1/18 Tri-Mix at 30 pap/2 phent/40 pge @0.3ml supp w/0.1-0.2ml 60mcg/ml PGE1 on occasion for a longer session. DE/Anorgasmia setting in since 5/19


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