Anorgasmia (Failure to achieve orgasm)

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BigEyes
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Re: Anorgasmia (Failure to achieve orgasm)

Postby BigEyes » Thu Jun 07, 2018 2:32 pm

Hey RedandWhite

Unfortuately, aging tends to make nerves less sensitive. Typically takes more stimulation for an orgasm as we get older. This is usually from nerve deterioration due to insufficient blood flow in and around them, which is also a byproduct of aging. I use a natural regimen of vitamins, minerals and herbals to support blood circulation. It's not a cure, but theoretically helps.

Glad you've found a way. I have seen many of my clients give up when they have this sort of issue. Personally, I sometimes have difficulty achieving orgasm during intercourse, but it is very enjoyable to stay aroused for a long time and NOT have an orgasm. My wife certainly likes the lengthy action, and is very willing to use oral or manual stimulation to bring me to orgasm afterward.

Younger guys, that go off in 10 min or less, don't know what they are missing!!! ..... :D

BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012

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Larry10625
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Re: Anorgasmia (Failure to achieve orgasm)

Postby Larry10625 » Thu Jun 07, 2018 4:31 pm

BigEyes wrote:Hey RedandWhite

Unfortuately, aging tends to make nerves less sensitive. Typically takes more stimulation for an orgasm as we get older. This is usually from nerve deterioration due to insufficient blood flow in and around them, which is also a byproduct of aging. I use a natural regimen of vitamins, minerals and herbals to support blood circulation. It's not a cure, but theoretically helps.

Glad you've found a way. I have seen many of my clients give up when they have this sort of issue. Personally, I sometimes have difficulty achieving orgasm during intercourse, but it is very enjoyable to stay aroused for a long time and NOT have an orgasm. My wife certainly likes the lengthy action, and is very willing to use oral or manual stimulation to bring me to orgasm afterward.

Younger guys, that go off in 10 min or less, don't know what they are missing!!! ..... :D

BigEyes



Geez, before ED I would have been happy with 10 minutes... not anymore, I'm lasting around 30 minutes and loving every single second of it, right up to my geyser..(well most times). :D

Larry
51 years old, married 29 years. Implanted Mar 30/17 by Dr. Brock of London, Ont, CANADA. (AMS 700 CX 18 + 2). Had implant removed Apr 29/17 due to Septic Shock. Liposuction By Dr. Gan and re-implant by Dr. Brock (AMS LGX 15 + 2) Dec 14/17.

Stew52
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Re: Anorgasmia (Failure to achieve orgasm)

Postby Stew52 » Tue Sep 18, 2018 10:28 pm

Gents, I have read this thread and some of the other related ones. Thanks for the insights. I feel like I have had slowly advancing "anorgasmia" for a few years. The bad news is that OCCASIONALLY but with increasing frequency, even after heroic measures, I can not ejaculate. The good news for my wife is that any tendency for an "early out" premature rarely happens now, in fact it is testing the limits of her endurance to tolerate continuous orgasms for 30-60 minutes (she is exhausted and wasted, "dazed and confused", so we are adjusting down a bit and I just do without an E).

I do find that if we have sex every 2-3 days, it is harder to ejaculate and can take 4-8 days to pop, but when I do, Bam, it's great. At first my wife was concerned but I suggested it was her turn to be dazed and confused now and I got pleasure in pleasuring her. It's the new normal so enjoy it. She's OK with that now but concerned. We'd like to "come together" as the Beatles said.

In perusing the thread's comments and using my own thoughts I have come up with the following list of possible contributing causes. Unfortunately it is a bit long and becomes hard to ascertain a cause, especially with some facts unknown.

1. Getting older and just old dulled nerves (less capillary blood flow)
2. Nerve damage from advancing peripheral neuropathy (diabetic, idiopathic or MS, etc.)
3. Neuropathy from drugs like Levaquin, Cipro, others?
4. Nerve trunk damage due to overpumping, over "PT", surgery or injury
5. Some effect from LT use of ED pills??
6. Some effect from ED injections/pain/ache - no doubt on this for me
7. Too much PGE1
8. Too much masturbation (time to reload)
9. Too much sex for age (time to reload)
10. Not enough liquids
11. A vasectomy?
12. Enlarged prostate
13. Removed prostate
14. Needing more rhythm control in having sex, some women like it fast and hard
15. Effect of other drugs (e.g. Paxil/SSRI's), OTC or herbs (which?)
16. Less "wad" and urgency due to vasectomy
17. Less "wad" and urgency due to older age production
18. Recreational drug use
Add 19. Performance anxiety
Add 20. Injection of PGE near septum nerve bundle
??? Feel free to add

In this list several do now or have applied to me in the past (Paxil made me a beast). And many are unknowns. I wholeheartedly concur that higher doses of PGE1 really inhibits me, in fact if we plan a longer session (an overhaul versus a tune-up), I use more PGE1 for a longer hard boner and hence a delayed or no ejaculation deliberately.

So, if you don't really know the cause(s), how do you really treat it???

And, with the growth of injections, implants in older guys now, and longer longevity, is this becoming a bigger issue such that it deserves a separate folder (since PE has one)?
Last edited by Stew52 on Fri Sep 28, 2018 11:10 pm, edited 1 time in total.
NOT an MD. 66, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr (35mcg PGE). 1/18 Using Tri-Mix at 30 pap/2 phent/40 pge @ 0.3ml. Supp w/ 0.1-0.2ml 60 mcg/ml PGE1 on occasion for a longer session. Anorgasmia setting in.

BigEyes
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Re: Anorgasmia (Failure to achieve orgasm)

Postby BigEyes » Wed Sep 19, 2018 10:37 am

Stew52

Nice job of compilation. I think you hit just about all of the possibilities.

I've done some research on this and can specifically confirm #7 -- too much PGE-1.
I have confirmed this thru extensive testing and dose control. If you use PGE-1, use just enough for a decent erection. More is definitely not better.

Also, #18. Recreational drug use. Marijuana enhances sexual ability for many individuals, sometimes making orgasm more achievable. However, the same applies as above -- more is not better.

BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012

Reggieman
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Re: Anorgasmia (Failure to achieve orgasm)

Postby Reggieman » Wed Sep 19, 2018 1:09 pm

In my case I believe nerve damage from the prostatectomy caused my anorgasmia. Oxytocin has been debunked as an effective drug as per a medical review I read a few months ago. Cabergoline, Oxytocin and Buspirone have nor worked for me either.
Retired. R.P. June 2016 at UCSF. Bilateral nerve sparing robotic surgery. Use .15cc of Bimix twice weekly. Still have some incontinence and not improving. Other side effects: anorgasmia & decreased penis sensitivity.

BigEyes
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Re: Anorgasmia (Failure to achieve orgasm)

Postby BigEyes » Wed Sep 19, 2018 2:20 pm

Hey Reggieman

Cabergoline is a drug that reduces prolactin levels. If high prolactin is your problem, it might work, otherwise it is useless (and side effects are real nasty)

Oxytocin is a natural brain chemical that soars at orgasm. However, aside from a single study I read (which wasn't very definitive), it doesn't seem to be very effective. Again, if your baseline level is very low, it might help.

Buspirone is an antianxiety drug similar in effect to Zanex. I doubt it would do anything if the anorgasmia is either prostate or age related.
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012

Reggieman
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Re: Anorgasmia (Failure to achieve orgasm)

Postby Reggieman » Wed Sep 19, 2018 2:26 pm

Bigeyes- I suffered no side effects from any of the drugs you mentioned...aside from lightening my wallet.
Retired. R.P. June 2016 at UCSF. Bilateral nerve sparing robotic surgery. Use .15cc of Bimix twice weekly. Still have some incontinence and not improving. Other side effects: anorgasmia & decreased penis sensitivity.

Stew52
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Re: Anorgasmia (Failure to achieve orgasm)

Postby Stew52 » Wed Sep 19, 2018 10:32 pm

BigEyes wrote:Stew52

Nice job of compilation. I think you hit just about all of the possibilities.

I've done some research on this and can specifically confirm #7 -- too much PGE-1.
I have confirmed this thru extensive testing and dose control. If you use PGE-1, use just enough for a decent erection. More is definitely not better.

Also, #18. Recreational drug use. Marijuana enhances sexual ability for many individuals, sometimes making orgasm more achievable. However, the same applies as above -- more is not better.

BigEyes


Not all on the list are "proven" some just suspected, at least by me.

I hit numbers 1 (older), 2, 3 (idiopathic in feet), 5??, 6, 7 (on occasion), 9 (shorter than ~3 days), 11??, 14 (really likes it hard and fast), 15 (Paxil once, Sudafed for sinus infections occasionally, others ???), 16/17 (@66 y/o). So I hit a lot of possible and known triggers. I can manage the latter "known" triggers. And some are unknowns including like Rx, OTC and supplements. A known common side-effect of fluoroquinolones is nerve damage and I've been on Cipro and Levaqin a lot.

Key for me at this time are time to ejaculation less than 3-4 days and higher dose of PGE1, and 14 ironically (rhythm). But one can also use that to advantage for a longer session for Wifey :D :shock: but I just may not cum that time. After a month layoff on vacation with wife and two teenage grandaughters in Europe (close quarters), I am getting back up to speed and find now after a very aggressive "recovery" (every 2 1/2 days on avg) :D :D that willey is in tuned-up shape and can actually do the job now with far less PGE1 so I am ramping the mix down. Morning wood and PHO's are quite common now. :o That is a nice finding.

Thaks for all the ideas on treatments. I do L-Arginine , Propionyl-L-Carnitine, Siberian Ginseng, and am restarting Alfa Lipoic Acid for the foot neuropathy.
Last edited by Stew52 on Thu Sep 20, 2018 10:36 pm, edited 1 time in total.
NOT an MD. 66, CenTX US. Inj since 12/16 a yr after pills stopped working. Caverject for a yr (35mcg PGE). 1/18 Using Tri-Mix at 30 pap/2 phent/40 pge @ 0.3ml. Supp w/ 0.1-0.2ml 60 mcg/ml PGE1 on occasion for a longer session. Anorgasmia setting in.

60s_surfer
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Re: Anorgasmia (Failure to achieve orgasm)

Postby 60s_surfer » Thu Sep 20, 2018 7:24 pm

Let me contribute my $0.02 to this thread. I have had continuing problems with delayed ejaculation since at least 2012. I was prescribed cabergoline by a sexual medicine specalist; it helps somewhat but the amount I can take is limited because it makes me tired. I find that 1/8 mg per day is OK but anything more is too much. This requires me to cut the little pills in quarters, which is a bit of a pain. I also have the suspicion that too much PGE-1 inhibits ejaculation although my sexual medicine specialist says it shouldn't. There is also a known problem with alpha blockers and ejaculation when the alpha blocker is prescribed for BPH. Phentolamine, unfortunately, is an alpha blocker, although is it a selective one whereas the ones used for BPH are unselective. Still, I keep wondering if phentolamine has any contribution to my problem. I do find that sub-lingual oxytocin (250 IU) one hour before lovemaking helps. This mostly because it mellows me out, reducing my anxiety about whether I will be able to ejaculate this time. I also use one dose of Natesto, nasal testosterone, when I take the oxytocin. When I first started this, it really helped but my body has now gotten used to it and it is no longer as effective. As a suggestion to Franktalk, I would like to see Delayed Ejaculation have its own forum, just as Premature Ejaculation does so that we could gather together all the threads on this. Finally, where does one find either apomorphine or mucuna puriens? I am always especially concerned about botanicals because one never knows how uniform they are or how to find the proper dose.
71 years old in 2018; married 49 years. ED since 2001. PD5 inhibitors (Viagra, etc.) worked with increasing dosages until side effects got too bad by 2017. Now using Trimix injections. Delayed ejaculation has been a continuing problem since 2012.

BigEyes
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Re: Anorgasmia (Failure to achieve orgasm)

Postby BigEyes » Fri Sep 21, 2018 11:51 am

Hey 60sSurfer

Thanks for your 2 cents worth. Here's mine. After extensive testing on myself as well as some of my clients, I am pretty sure that an increased level of PGE-1 can cause Anorgasmia. I typically use about 50mcg intraurethrally with OK orgasmic response. At 100 mcg orgasms are iffy. At 150mcg or higher they are non-existent regardless of intensity of stimulation.

Regarding oxytocin - I have used up to 200 IU intranasal. Seems to help a little with mood, but otherwise an unremarkable effect.

You might want to try using 2-3 mg/day of Boron. A trace mineral that helps balance hormones and lowers SHBG. Check this extensive article on Boron.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/

As far as Mucuna Puriens. It is available on various sites. I stock it for my clients especially those with Parkinsons. It helps lower prolactin levels and thereby helps the action of free T.

Moderator -- I started this thread and I agree with 60sSurfer wholeheartedly that we need a forum on Delayed Ejaculation and Anorgasmia

BigEyes
Doctor of Naturopathy (N.D.) and Herbalist. ED and occasional Anorgasmia from perineal surgery for rectal cancer Dec. 2012


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